Migraine is a prevalent primary headache disorder and is usually considered as benign.
However, structural and functional changes in the brain of individuals with migraine have …

Hemiplegic migraine (HM) is a clinically and genetically heterogeneous condition with
attacks of headache and motor weakness which may be associated with impaired …

Cortical spreading depression (CSD), a wave of depolarization followed by depression of
cortical activity, is a pathophysiological process implicated in migraine with aura and various …

Background Migraine is a common debilitating condition whose main attributes are severe
recurrent headaches with accompanying sensitivity to light and sound, nausea and vomiting …

Migraine is a complex neurovascular pain disorder linked to the meninges, a border tissue
innervated by neuropeptide-containing primary afferent fibers chiefly from the trigeminal …

Background Migraine is considered a multifactorial genetic disorder. Different platforms and
methods are used to unravel the genetic basis of migraine. Initially, linkage analysis in …

Migraine with aura is a common but poorly understood sensory circuit disorder. Monogenic
models allow an opportunity to investigate its mechanisms, including spreading …

Migraine is a common brain disorder with a large genetic component. Of the two main
migraine types, migraine with aura and migraine without aura, the genetic underpinning in …

Targeting CGRP-pathways has substantially expanded our options for treating individuals
with migraine. Although the efficacy of these drugs on migraine aura is yet to be fully …

Migraine and major depression are debilitating disorders with high lifetime prevalence rates.
Interestingly these disorders are highly comorbid and show significant heritability …