Novel diagnostic technologies, including nanotechnology, microfluidics,-omics science, next-
generation sequencing, genomics big data, and machine learning, could contribute to …

HIV drug resistance is a major global challenge to successful and sustainable antiretroviral
therapy. Next-generation sequencing (NGS)-based HIV drug resistance (HIVDR) assays …

Broadly neutralizing antibodies (bNAbs) for HIV-1 prevention or cure strategies must inhibit
transmitted/founder and reservoir viruses. Establishing sensitivity of circulating viruses to …

The extensive genetic diversity of HIV-1 is a major challenge for the prevention and
treatment of HIV-1 infections. Subtype C accounts for most of the HIV-1 infections in the …

Ritonavir-boosted atazanavir is an option for second-line therapy in low-and middle-income
countries (LMICs). We analyzed publicly available HIV-1 protease sequences from …

Across sub-Saharan Africa, key populations with elevated HIV-1 incidence and/or
prevalence have been identified, but their contribution to disease spread remains unclear …

Synthetic biology (SynBio) is a rapidly advancing multidisciplinary field in which South
American countries such as Chile, Argentina, and Brazil have made notable contributions …

Objectives The HIV-1 genetic diversity and the presence of transmitted drug resistance
mutations (TDRMs) against integrase strand transfer inhibitors (INSTIs) were assessed …

Viruses change constantly during replication, leading to high intra-species diversity.
Although many changes are neutral or deleterious, some can confer on the virus different …

Background Antiretroviral therapy has revolutionized HIV treatment, increasing quality and
life expectancy of people living with HIV (PLWH). However, the expansion of treatment has …