Sex differences in stress-related psychiatric disorders: neurobiological perspectives

DA Bangasser, RJ Valentino - Frontiers in neuroendocrinology, 2014 - Elsevier
Stress is associated with the onset and severity of several psychiatric disorders that occur
more frequently in women than men, including posttraumatic stress disorder (PTSD) and …

Predicting PTSD: pre-existing vulnerabilities in glucocorticoid-signaling and implications for preventive interventions

M van Zuiden, A Kavelaars, E Geuze, M Olff… - Brain, Behavior, and …, 2013 - Elsevier
Posttraumatic stress disorder (PTSD) is an anxiety disorder that may develop in response to
a traumatic event. Approximately 10% of trauma-exposed individuals subsequently develop …

Glucocorticoid receptor pathway components predict posttraumatic stress disorder symptom development: a prospective study

M Van Zuiden, E Geuze, HLDM Willemen… - Biological …, 2012 - Elsevier
BACKGROUND: Biological correlates of posttraumatic stress disorder (PTSD) have mostly
been studied using cross-sectional or posttrauma prospective designs. Therefore, it remains …

Pre-existing high glucocorticoid receptor number predicting development of posttraumatic stress symptoms after military deployment

M Van Zuiden, E Geuze… - American Journal of …, 2011 - Am Psychiatric Assoc
Objective: The development of posttraumatic stress disorder (PTSD) is influenced by
preexisting vulnerability factors. The authors aimed at identifying a preexisting biomarker …

Biomarker approaches in major depressive disorder evaluated in the context of current hypotheses

MC Jentsch, EM Van Buel, FJ Bosker… - Biomarkers in …, 2015 - Taylor & Francis
Major depressive disorder is a heterogeneous disorder, mostly diagnosed on the basis of
symptomatic criteria alone. It would be of great help when specific biomarkers for various …

The Historical Progression of Positron Emission Tomography Research in Neuroendocrinology

J Bini - Frontiers in Neuroendocrinology, 2023 - Elsevier
The rapid and continual development of a number of radiopharmaceuticals targeting
different receptor, enzyme and small molecule systems has fostered Positron Emission …

Imaging brain cortisol regulation in PTSD with a target for 11β-hydroxysteroid dehydrogenase type 1

S Bhatt, AT Hillmer, A Rusowicz… - The Journal of …, 2021 - Am Soc Clin Investig
BACKGROUND Investigations of stress dysregulation in posttraumatic stress disorder
(PTSD) have focused on peripheral cortisol, but none have examined cortisol in the human …

PET imaging agents (FES, FFNP, and FDHT) for estrogen, androgen, and progesterone receptors to improve management of breast and prostate cancers by …

JA Katzenellenbogen - Cancers, 2020 - mdpi.com
Many breast and prostate cancers are driven by the action of steroid hormones on their
cognate receptors in primary tumors and in metastases, and endocrine therapies that inhibit …

[HTML][HTML] Glucocorticoid receptor number predicts increase in amygdala activity after severe stress

E Geuze, GA van Wingen, M van Zuiden… - …, 2012 - Elsevier
INTRODUCTION: Individuals who are exposed to a traumatic event are at increased risk of
developing psychiatric disorders such as posttraumatic stress disorder (PTSD). Studies have …

Nuclear receptor imaging in vivo—clinical and research advances

EE Parent, AM Fowler - Journal of the Endocrine Society, 2023 - academic.oup.com
Nuclear receptors are transcription factors that function in normal physiology and play
important roles in diseases such as cancer, inflammation, and diabetes. Noninvasive …