Reprogramming of intestinal glucose metabolism and glycemic control in rats after gastric bypass

N Saeidi, L Meoli, E Nestoridi, NK Gupta, S Kvas… - Science, 2013 - science.org
The resolution of type 2 diabetes after Roux-en-Y gastric bypass (RYGB) attests to the
important role of the gastrointestinal tract in glucose homeostasis. Previous studies in RYGB …

Regulation of glucose homeostasis by GLP-1

P Nadkarni, OG Chepurny, GG Holz - Progress in molecular biology and …, 2014 - Elsevier
Abstract Glucagon-like peptide-1 (7–36) amide (GLP-1) is a secreted peptide that acts as a
key determinant of blood glucose homeostasis by virtue of its abilities to slow gastric …

Microvascular outcomes in patients with diabetes after bariatric surgery versus usual care: a matched cohort study

R O'Brien, E Johnson, S Haneuse… - Annals of internal …, 2018 - acpjournals.org
Background: Bariatric surgery improves glycemic control in patients with type 2 diabetes
mellitus (T2DM), but less is known about microvascular outcomes. Objective: To investigate …

Weight loss strategies for treatment of obesity

RF Kushner - Progress in cardiovascular diseases, 2014 - Elsevier
Obesity is one of the most serious and prevalent non-communicable diseases of the 21st
century. It is also a patient-centered condition in which affected individuals seek treatment …

A novel dual glucagonlike peptide and glucagon receptor agonist SAR425899: results of randomized, placebocontrolled firstinhuman and firstinpatient trials

J Tillner, MG Posch, F Wagner… - Diabetes, Obesity …, 2019 - Wiley Online Library
Aims To evaluate the safety, pharmacokinetics and pharmacodynamics of SAR425899, a
novel polypeptide, active as an agonist at both the glucagonlike peptide1 receptor (GLP …

Metabolic effects of bariatric surgery in patients with moderate obesity and type 2 diabetes: analysis of a randomized control trial comparing surgery with intensive …

SR Kashyap, DL Bhatt, K Wolski, RM Watanabe… - Diabetes …, 2013 - Am Diabetes Assoc
OBJECTIVE To evaluate the effects of two bariatric procedures versus intensive medical
therapy (IMT) on β-cell function and body composition. RESEARCH DESIGN AND …

TFOS Lifestyle: impact of nutrition on the ocular surface

M Markoulli, S Ahmad, J Arcot, R Arita… - The ocular …, 2023 - Elsevier
Nutrients, required by human bodies to perform life-sustaining functions, are obtained from
the diet. They are broadly classified into macronutrients (carbohydrates, lipids, and proteins) …

[HTML][HTML] Ожирение

ИИ Дедов, НГ Мокрышева, ГА Мельниченко… - Consilium …, 2021 - cyberleninka.ru
В декабре 2020 г. Научно-практическим советом Минздрава России были утверждены
клинические рекомендации «Ожирение», разработанные Российской ассоциацией …

Exaggerated glucagon-like peptide 1 response is important for improved β-cell function and glucose tolerance after Roux-en-Y gastric bypass in patients with type 2 …

NB Jørgensen, C Dirksen, KN Bojsen-Møller… - Diabetes, 2013 - Am Diabetes Assoc
β-Cell function improves in patients with type 2 diabetes in response to an oral glucose
stimulus after Roux-en-Y gastric bypass (RYGB) surgery. This has been linked to the …

Acute and long-term effects of Roux-en-Y gastric bypass on glucose metabolism in subjects with Type 2 diabetes and normal glucose tolerance

NB Jørgensen, SH Jacobsen… - American Journal …, 2012 - journals.physiology.org
Our aim was to study the potential mechanisms responsible for the improvement in glucose
control in Type 2 diabetes (T2D) within days after Roux-en-Y gastric bypass (RYGB) …