Brain fog in hypothyroidism: what is it, how is it measured, and what can be done about it

MH Samuels, LJ Bernstein - Thyroid, 2022 - liebertpub.com
Background: Some levothyroxine (LT4)-treated hypothyroid patients report a constellation of
persistent and distressing cognitive symptoms that has been termed brain fog. This narrative …

New Horizons: the value of UK Biobank to research on endocrine and metabolic disorders

J Bešević, B Lacey, M Conroy… - The Journal of …, 2022 - academic.oup.com
UK Biobank is an intensively characterized prospective study of 500 000 men and women,
aged 40 to 69 years when recruited, between 2006 and 2010, from the general population of …

Impaired sensitivity to thyroid hormones and carotid plaque in patients with coronary heart disease: a RCSCD-TCM study in China

Y Liu, Z Li, T Yang, L Li, L Yu, F Liu, T Ni… - Frontiers in …, 2022 - frontiersin.org
Context Previous studies on the association between thyroid function and carotid plaque
have shown contradictory results, which may be attributable to the sensitivity to thyroid …

[HTML][HTML] Activation of cholinergic basal forebrain neurons improved cognitive functions in adult-onset hypothyroid mice

YX Xu, C Wang, XD Li, WL Guo, GY Liu… - Biomedicine & …, 2022 - Elsevier
Cognitive dysfunction is common in hypothyroid patients, even after undergoing sufficient
levothyroxine (LT4) replacement therapy for euthyroid. Our previous studies indicated that …

[HTML][HTML] The correlation between thyroid function, frontal gray matter, and executive function in patients with major depressive disorder

S Zhao, Y Xia, Y Huang, H Zou, X Wang… - Frontiers in …, 2021 - frontiersin.org
The present study was aimed to investigate the relationships between serum thyroid
hormones (THs), frontal gray matter volume, and executive function in selected patients with …

Interrelationships among growth hormone, thyroid function, and endocrine-disrupting chemicals on the susceptibility to attention-deficit/hyperactivity disorder

LJ Wang, YH Huang, WJ Chou, SY Lee… - European Child & …, 2023 - Springer
Abnormal growth hormones and thyroid function may be linked to pathophysiology of
attention-deficit/hyperactivity disorder (ADHD). Phthalates and bisphenol-A (BPA), two …

[HTML][HTML] Gray matter reduction is associated with cognitive dysfunction in depressed patients comorbid with subclinical hypothyroidism

S Zhao, Y Du, Y Zhang, X Wang, Y Xia… - Frontiers in Aging …, 2023 - frontiersin.org
Introduction To explore the association between regional gray matter volume (GMV) and
cognitive impairments and ascertain whether the regional brain alterations related to …

Controlled Antenatal Thyroid Screening Study III: Effects of gestational thyroid status on adolescent brain morphology

A Scholz, CB McNabb, L Bloomfield… - The Journal of …, 2024 - academic.oup.com
Context Children born to mothers with gestational hypo-or hyperthyroidism may have
increased risk of adverse neurodevelopmental outcomes. However, the effects of maternal …

Growth hormone and thyroid function in children with attention deficit hyperactivity disorder undergoing drug therapy

LJ Wang, YH Huang, WJ Chou… - The Journal of Clinical …, 2022 - academic.oup.com
Context The trends in hormone indices of children with attention deficit hyperactivity disorder
(ADHD) who received long-term medication treatment remains controversial. Objective This …

Mapping Thyroid Hormone Action in the Human Brain

F Salas-Lucia - Thyroid, 2024 - liebertpub.com
Background: Normal brain development, mood, and cognitive functions depend on thyroid
hormone (TH) action. However, little is known about how TH mediates its actions in the …