Conspectus Carbohydrates are the most abundant biopolymers on earth and part of every
living creature. Glycans are essential as materials for nutrition and for information transfer in …

Virus infection is an intricate process that requires the concerted action of both viral and host
cell components. Entry of viruses into cells is initiated by interactions between viral proteins …

Written by more than 400 subject experts representing diverse academic and applied
domains, this multidisciplinary resource surveys the vanguard of biomaterials and …

Glycosaminoglycan (GAG) side chains endow extracellular matrix proteoglycans with
diversity and complexity based upon the length, composition and charge distribution of the …

To meet the growing need for tissue replacement materials for our aging population, the
development of new adaptive biomaterials is essential. The tissues with the highest demand …

Carbohydrates are the most prevalent class of biopolymers on earth. Bound to proteins and
lipids, carbohydrates form four structurally and functionally distinct, biologically significant …

Heparin (HP) and heparan sulfate (HS) are linear, anionically charged polysaccharides well-
known for their diverse biological activities. While HP is generally localized in mast cells and …

The rates of enzyme reactions fall within a relatively narrow range. To estimate the rate
enhancements produced by enzymes, and their expected affinities for transition state analog …

The orderly development of the nervous system is characterized by phases of cell
proliferation and differentiation, neural migration, axonal outgrowth and synapse formation …

The cell surface displays a complex array of oligosaccharides, glycoproteins, and
glycolipids. This diverse mixture of glycans contains a wealth of information, modulating a …