Somatosensory and autonomic neuronal regulation of the immune response

S Udit, K Blake, IM Chiu - Nature Reviews Neuroscience, 2022 - nature.com
Bidirectional communication between the peripheral nervous system (PNS) and the immune
system is a crucial part of an effective but balanced mammalian response to invading …

[HTML][HTML] Mechanisms and therapeutic relevance of neuro-immune communication

SS Chavan, VA Pavlov, KJ Tracey - Immunity, 2017 - cell.com
Active research at the frontiers of immunology and neuroscience has identified multiple
points of interaction and communication between the immune system and the nervous …

Molecular and functional neuroscience in immunity

VA Pavlov, SS Chavan, KJ Tracey - Annual review of …, 2018 - annualreviews.org
The nervous system regulates immunity and inflammation. The molecular detection of
pathogen fragments, cytokines, and other immune molecules by sensory neurons generates …

Neuroprosthetic baroreflex controls haemodynamics after spinal cord injury

JW Squair, M Gautier, L Mahe, JE Soriano, A Rowald… - Nature, 2021 - nature.com
Spinal cord injury (SCI) induces haemodynamic instability that threatens survival,–, impairs
neurological recovery,, increases the risk of cardiovascular disease,, and reduces quality of …

Neural regulation of immunity: molecular mechanisms and clinical translation

VA Pavlov, KJ Tracey - Nature neuroscience, 2017 - nature.com
Studies bridging neuroscience and immunology have identified neural pathways that
regulate immunity and inflammation. Recent research using methodological advances in …

[HTML][HTML] Immune response following traumatic spinal cord injury: Pathophysiology and therapies

RC Sterner, RM Sterner - Frontiers in immunology, 2023 - frontiersin.org
Traumatic spinal cord injury (SCI) is a devastating condition that is often associated with
significant loss of function and/or permanent disability. The pathophysiology of SCI is …

Autonomic dysreflexia after spinal cord injury: Systemic pathophysiology and methods of management

KC Eldahan, AG Rabchevsky - Autonomic Neuroscience, 2018 - Elsevier
Traumatic spinal cord injury (SCI) has widespread physiological effects beyond the
disruption of sensory and motor function, notably the loss of normal autonomic and …

[HTML][HTML] Corticospinal circuits from the sensory and motor cortices differentially regulate skilled movements through distinct spinal interneurons

M Ueno, Y Nakamura, J Li, Z Gu, J Niehaus… - Cell reports, 2018 - cell.com
Little is known about the organizational and functional connectivity of the corticospinal (CS)
circuits that are essential for voluntary movement. Here, we map the connectivity between …

Spinal cord injury-induced immunodeficiency is mediated by a sympathetic-neuroendocrine adrenal reflex

H Prüss, A Tedeschi, A Thiriot, L Lynch… - Nature …, 2017 - nature.com
Acute spinal cord injury (SCI) causes systemic immunosuppression and life-threatening
infections, thought to result from noradrenergic overactivation and excess glucocorticoid …

Neuroimmunological therapies for treating spinal cord injury: Evidence and future perspectives

JCT Chio, KJ Xu, P Popovich, S David… - Experimental …, 2021 - Elsevier
Spinal cord injury (SCI) has a complex pathophysiology. Following the initial physical
trauma to the spinal cord, which may cause vascular disruption, hemorrhage, mechanical …