The mammalian brown fat inducible thioesterase variant 2 (BFIT2), also known as ACOT11,
is a multimodular protein containing two consecutive hotdog-fold domains and a C-terminal …

Among various therapeutic approaches for stroke, treatment with human umbilical cord
mesenchymal stem cells (hUC-MSCs) has acquired some promising results. However, the …

Many lineage-defining (nodal) mutations possess high functionality. However, differentiating
adaptive nodal mutations from those that are functionally compensated remains challenging …

Invaded species often can rapidly expand and establish in novel environments through
adaptive evolution, resulting in devastating effects on native communities. However, it is …

Dinoflagellates play important roles in ecosystems as primary producers and consumers
making natural products that can benefit or harm environmental and human health but are …

Gene transcripts or mRNAs and long noncoding RNAs (lncRNAs) are differentially
expressed during porcine skeletal muscle development. However, only a few studies have …

Abstract Objective Thioesterase superfamily member 1 (Them1) is a long chain acyl-CoA
thioesterase comprising two N-terminal HotDog fold enzymatic domains linked to a C …

We have performed exome-wide association studies to identify genetic variants that
influence renal function-related traits or confer susceptibility to chronic kidney disease or …

Cold-induced thermogenesis plays an important role in the survival of lambs exposed to low
air temperatures. The liver produces and mediates heat production in mammals; however, to …

Background Diet-induced metabolic dysfunction precedes multiple disease states including
diabetes, heart disease, and vascular dysfunction. The critical role of the vasculature in …