Psychosis superspectrum I: Nosology, etiology, and lifespan development
This review describes the Hierarchical Taxonomy of Psychopathology (HiTOP) model of
psychosis-related psychopathology, the psychosis superspectrum. The HiTOP psychosis …
psychosis-related psychopathology, the psychosis superspectrum. The HiTOP psychosis …
Prevalence of individuals at clinical high-risk of psychosis in the general population and clinical samples: systematic review and meta-analysis
G Salazar de Pablo, SW Woods, G Drymonitou… - Brain sciences, 2021 - mdpi.com
(1) The consistency and magnitude of the prevalence of Clinical High-Risk for Psychosis
(CHR-P) individuals are undetermined, limiting efficient detection of cases. We aimed to …
(CHR-P) individuals are undetermined, limiting efficient detection of cases. We aimed to …
Prevention of psychosis: advances in detection, prognosis, and intervention
Importance Detection, prognosis, and indicated interventions in individuals at clinical high
risk for psychosis (CHR-P) are key components of preventive psychiatry. Objective To …
risk for psychosis (CHR-P) are key components of preventive psychiatry. Objective To …
Beyond the “at risk mental state” concept: transitioning to transdiagnostic psychiatry
PD McGorry, JA Hartmann, R Spooner… - World …, 2018 - Wiley Online Library
The “at risk mental state” for psychosis approach has been a catalytic, highly productive
research paradigm over the last 25 years. In this paper we review that paradigm and …
research paradigm over the last 25 years. In this paper we review that paradigm and …
Multimodal machine learning workflows for prediction of psychosis in patients with clinical high-risk syndromes and recent-onset depression
Importance Diverse models have been developed to predict psychosis in patients with
clinical high-risk (CHR) states. Whether prediction can be improved by efficiently combining …
clinical high-risk (CHR) states. Whether prediction can be improved by efficiently combining …
Clinical validity of DSM-5 attenuated psychosis syndrome: advances in diagnosis, prognosis, and treatment
Importance Since the release of theDSM-5diagnosis of attenuated psychosis syndrome
(DSM-5–APS) in 2013, several research studies have investigated its clinical validity …
(DSM-5–APS) in 2013, several research studies have investigated its clinical validity …
Improving the detection of individuals at clinical risk for psychosis in the community, primary and secondary care: an integrated evidence-based approach
P Fusar-Poli, SA Sullivan, JL Shah… - Frontiers in psychiatry, 2019 - frontiersin.org
Background: The first rate-limiting step for improving outcomes of psychosis through
preventive interventions in people at clinical high risk for psychosis (CHR-P) is the ability to …
preventive interventions in people at clinical high risk for psychosis (CHR-P) is the ability to …
Pluripotential risk and clinical staging: theoretical considerations and preliminary data from a transdiagnostic risk identification approach
JA Hartmann, PD McGorry, L Destree… - Frontiers in …, 2021 - frontiersin.org
Most psychiatric disorders develop during adolescence and young adulthood and are
preceded by a phase during which attenuated or episodic symptoms and functional decline …
preceded by a phase during which attenuated or episodic symptoms and functional decline …
Wireless, noninvasive therapeutic drug monitoring system for saliva measurement toward medication management of schizophrenia
As an efficient patient management tool of precision medicine, decentralized therapeutic
drug monitoring (TDM) provides new vision for therapy adherence and health management …
drug monitoring (TDM) provides new vision for therapy adherence and health management …
MicroRNAs in the Onset of Schizophrenia
KT Thomas, SS Zakharenko - Cells, 2021 - mdpi.com
Mounting evidence implicates microRNAs (miRNAs) in the pathology of schizophrenia.
These small noncoding RNAs bind to mRNAs containing complementary sequences and …
These small noncoding RNAs bind to mRNAs containing complementary sequences and …