Cell invasion into the surrounding extracellular matrix or across tissue boundaries and
endothelial barriers occurs in both physiological and pathological scenarios such as …

Cell migration is an essential process, both in unicellular organisms such as amoeba and as
individual or collective motility in highly developed multicellular organisms like mammals. It …

The minimal structural unit of a solid tumor is a single cell or a cellular compartment such as
the nucleus. A closer look inside the cells reveals that there are functional compartments or …

Endothelial cells line blood vessels and provide a dynamic interface between the blood and
tissues. They remodel to allow leukocytes, fluid and small molecules to enter tissues during …

Cells migrate in multiple different ways depending on their environment, which includes the
extracellular matrix composition, interactions with other cells, and chemical stimuli. For all …

Actin remodeling is at the heart of the response of cells to external or internal stimuli,
allowing a variety of membrane protrusions to form. Fifteen years ago, tunneling nanotubes …

Various cellular processes (including cell motility) are driven by the regulated, polarized
assembly of actin filaments into distinct force-producing arrays of defined size and …

Metastasis causes death of 90% of cancer patients, so it is the most significant issue
associated with cancer disease. Thus, it is no surprise that many researchers are trying to …

Actin is a versatile and ubiquitous cytoskeletal protein that plays a major role in both the
establishment and the maintenance of neuronal polarity. For a long time, the most prominent …

The actin cytoskeleton is essential for cell mechanics and has increasingly been implicated
in the regulation of cell signalling. In B cells, the actin cytoskeleton is extensively coupled to …