Platelets are main drivers of thrombus formation. Besides platelet aggregate formation,
platelets interact with different blood cells such as red blood and white blood cells (RBCs …

Cardiovascular diseases (CVDs) account for over 17 million deaths globally each year, with
atherosclerosis as the underlying cause of most CVDs. Herein we describe the synthesis …

In chronic kidney disease (CKD), hyperphosphatemia is a key factor promoting medial
vascular calcification, a common complication associated with cardiovascular events and …

Background and aims Platelets are critically involved in tissue repair and regeneration,
which depend on their inflammatory properties and survival. SDF-1 ligates to CXCR4 and …

Thrombo-occlusive diseases such as myocardial infarction, ischemic stroke and deep vein
thrombosis with subsequent pulmonary embolism still represent a major health burden …

Platelets are cytoplasmatic fragments from bone marrow megakaryocytes present in blood.
In this work, we review the basis of platelet mechanisms, their participation in syndromes …

Abdominal aortic aneurysm (AAA) is a highly lethal vascular disease. The role of platelets in
AAA remains incompletely understood. Here we show that platelet ceramides, rather than …

The serum‐and glucocorticoid‐inducible kinase 1 (SGK 1) is expressed in megakaryocytes
and circulating platelets. In megakaryocytes, SGK 1 activates transcription factor nuclear …

ADAM17, a prominent member of the “Disintegrin and Metalloproteinase”(ADAM) family, is
an important regulator of endothelial cell proliferation and cell survival. The protease …

Evidence of the precise biological pathway responsible for acute cardiovascular events
triggered by particulate matter (PM) exposure from anthropogenic emissions is sparse. We …