[PDF][PDF] Platelets contribute to amyloid-b aggregation in cerebral vessels through integrin aIIbb3–induced outside-in signaling and clusterin release
L Donner, K Fälker, L Gremer, S Klinker, G Pagani… - 2016 - cpclab.uni-duesseldorf.de
Cerebral amyloid angiopathy (CAA) is a vascular dysfunction disorder characterized by
deposits of amyloid-b (Ab) in the walls of cerebral vessels. CAA and Ab deposition in the …
deposits of amyloid-b (Ab) in the walls of cerebral vessels. CAA and Ab deposition in the …
Effect of TGFβ on Na+/K+ ATPase activity in megakaryocytes
Z Hosseinzadeh, E Schmid, E Shumilina… - Biochemical and …, 2014 - Elsevier
Abstract The Na+/K+ ATPase generates the Na+ and K+ concentration gradients across the
plasma membrane and is thus essential for cellular electrolyte homeostasis, cell membrane …
plasma membrane and is thus essential for cellular electrolyte homeostasis, cell membrane …
Sirtuins, mitochondria, and the melatonergic pathway in Alzheimer's disease
G Anderson, M Maes - Sirtuin Biology in Medicine, 2021 - Elsevier
Alzheimer's disease (AD) has been the subject of extensive investigation as to its biological
underpinnings. However, this has produced little of therapeutic benefit or indeed provided …
underpinnings. However, this has produced little of therapeutic benefit or indeed provided …
Drug delivery systems based on blood cells
The use of drug delivery systems (DDSs) using biological carriers, especially blood cells is a
rapidly emerging field. The blood cells have many exceptional advantages, for example …
rapidly emerging field. The blood cells have many exceptional advantages, for example …
基于血小板及其膜的仿生递药系统研究进展
徐剑培, 徐群为, 王晓琪, 辛洪亮 - 中国药科大学学报, 2018 - jcpu.cpu.edu.cn
血小板是人体血液中重要的固有成分, 在机体各类生理反应中发挥重要作用. 近年来,
基于血小板及其膜的仿生新型药物传递系统备受关注. 与传统药物载体相比 …
基于血小板及其膜的仿生新型药物传递系统备受关注. 与传统药物载体相比 …
Significant Discovery of Tetrahydrothieno[3,2‐c]pyridine‐2‐carboxamide Analogs as Potent P2Y12 Receptor Antagonists
SB Bhalekar, SN Shelke - Chemistry & Biodiversity, 2019 - Wiley Online Library
A series of analogs containing tetrahydrothieno [3, 2‐c] pyridine‐2‐carboxamide as a
building block with numerous alicyclic and aromatic amines were synthesized. All analogs …
building block with numerous alicyclic and aromatic amines were synthesized. All analogs …
[HTML][HTML] Synthesis of 4-Methoxy-1, 3-Benzenediolylhydrazones and Evaluation of Their Anti-Platelet Aggregation Activity
C Wang, Y Wang, Q Deng, X Liu - Iranian Journal of …, 2019 - ncbi.nlm.nih.gov
In our present investigation, a series of novel 4-methoxy-1, 3-benzenediolyl-hydrazones
were designed and synthesized, and their ability to inhibit platelet aggregation was …
were designed and synthesized, and their ability to inhibit platelet aggregation was …
The Platelet PARs
A Arachiche, MT Nieman - Platelets in Thrombotic and Non-Thrombotic …, 2017 - Springer
The serine protease thrombin is a potent activator of platelets. It binds to two classes of
receptors, the GPIb-IX complex and protease-activated receptors (PARs). PARs constitute a …
receptors, the GPIb-IX complex and protease-activated receptors (PARs). PARs constitute a …
I. Morphological and nanomechanical studies of lipid bilayers composed of polymerizable and non-polymerizable lipids ii. Fluidity studies of platelet plasma …
NM Fonseka - 2019 - search.proquest.com
Two main projects are discussed in this dissertation. The first project: Morphological and
nanomechanical studies of planar supported lipid bilayers (PSLB) composed of …
nanomechanical studies of planar supported lipid bilayers (PSLB) composed of …
[PDF][PDF] Identification of novel clinical applications for acid sphingomyelinase inhibitors
N Beckmann - 2017 - core.ac.uk
2.4. 1 Background __________________________________… 23 2.4. 2 Pathophysiology
of rheumatoid arthritis _________________________________ 23 2.4. 2.1 Genetic and …
of rheumatoid arthritis _________________________________ 23 2.4. 2.1 Genetic and …