Although the first ancient DNA molecules were extracted more than three decades ago, the
first ancient nuclear genomes could only be characterized after high-throughput sequencing …

Mycobacterium tuberculosis (Mtb) is the causative agent of human tuberculosis (TB) which
primarily infects the macrophages. Nearly a quarter of the world's population is infected …

The origin of the medieval Black Death pandemic (ad 1346–1353) has been a topic of
continuous investigation because of the pandemic's extensive demographic impact and long …

Multiple sclerosis (MS) is a neuro-inflammatory and neurodegenerative disease that is most
prevalent in Northern Europe. Although it is known that inherited risk for MS is located within …

Tuberculosis (TB), usually caused by Mycobacterium tuberculosis bacteria, is the first cause
of death from an infectious disease at the worldwide scale, yet the mode and tempo of TB …

Tuberculosis (TB) remains one of the deadliest infectious diseases in human history,
prevailing even in the 21st century. The causative agents of TB are represented by a group …

Previous ancient DNA research has shown that Mycobacterium pinnipedii, which today
causes tuberculosis (TB) primarily in pinnipeds, infected human populations living in the …

The ability to sequence genomes from ancient biological material has provided a rich source
of information for evolutionary biology and engaged considerable public interest. Although …

Mycobacterium tuberculosis (M. tb) is a globally distributed, obligate pathogen of humans
that can be divided into seven clearly defined lineages. An emerging consensus places the …

This perspective draws on the record of ancient pathogen genomes and microbiomes
illuminating patterns of infectious disease over the course of the Holocene in order to …