Capsaicin inhibits Jurkat T-cell activation by blocking calcium entry current ICRAC
BS Fischer, D Qin, K Kim, TV McDonald - Journal of Pharmacology and …, 2001 - ASPET
Capacitative calcium entry (CCE) through stores-operated Ca2+ channels is an absolute
requirement for normal activation of T lymphocytes. Organic blockers/inhibitors of the …
requirement for normal activation of T lymphocytes. Organic blockers/inhibitors of the …
Screening of transient receptor potential canonical channel activators identifies novel neurotrophic piperazine compounds
S Sawamura, M Hatano, Y Takada, K Hino… - Molecular …, 2016 - ASPET
Transient receptor potential canonical (TRPC) proteins form Ca2+-permeable cation
channels activated upon stimulation of metabotropic receptors coupled to phospholipase C …
channels activated upon stimulation of metabotropic receptors coupled to phospholipase C …
Calcium-dependent fast depolarizing afterpotentials in vasopressin neurons in the rat supraoptic nucleus
R Teruyama, WE Armstrong - Journal of neurophysiology, 2007 - journals.physiology.org
Oxytocin (OT) and vasopressin (VP) synthesizing magnocellular cells (MNCs) in the
supraoptic nucleus (SON) display distinct firing patterns during the physiological demands …
supraoptic nucleus (SON) display distinct firing patterns during the physiological demands …
[PDF][PDF] Inhibition by capsazepine of resiniferatoxin-and capsaicin-induced contractions of guinea pig trachea.
JL Ellis, BJ Undem - Journal of Pharmacology and Experimental …, 1994 - Citeseer
The site of action of resiniferatoxin(RTX) and capsaicin and the pharmacological
consequences of the resultant tachykinin release were examined in the guinea pig trachea …
consequences of the resultant tachykinin release were examined in the guinea pig trachea …
Inhibition of low pH evoked activation of airway sensory nerves by capsazepine, a novel capsaicin-receptor antagonist
YP Lou, JM Lundberg - Biochemical and biophysical research …, 1992 - Elsevier
Low pH is a well known sensory irritant in pathological conditions such as inflammation. The
mechanisms underlying this low pH effect were therefore studied in the guinea pig. Acid …
mechanisms underlying this low pH effect were therefore studied in the guinea pig. Acid …
Different types of toxins targeting TRPV1 in pain
The transient receptor potential vanilloid 1 (TRPV1) channels are members of the transient
receptor potential (TRP) superfamily. Members of this family are expressed in primary …
receptor potential (TRP) superfamily. Members of this family are expressed in primary …
Comparison of the sedative, cognitive, and analgesic effects of nitrous oxide, sevoflurane, and ethanol
R Duarte, A McNeill, G Drummond… - British journal of …, 2008 - academic.oup.com
Background Anaesthetics which work by different mechanisms may have different patterns
of effect. Measurement of these patterns thus may elucidate their mechanisms of action and …
of effect. Measurement of these patterns thus may elucidate their mechanisms of action and …
Vanilloid receptor agonists potentiate the in vivo local anesthetic activity of percutaneously injected site 1 sodium channel blockers
DS Kohane, Y Kuang, NT Lu, R Langer… - The Journal of the …, 1999 - pubs.asahq.org
Background Capsaicin, the pungent ingredient in chili peppers, is a vanilloid with noxious
and analgesic effects that inhibits tetrodotoxin-resistant sodium currents. Because …
and analgesic effects that inhibits tetrodotoxin-resistant sodium currents. Because …
Participation of the spinal TRPV1 receptors in formalin‐evoked pain transduction: a study using a selective TRPV1 antagonist, iodo‐resiniferatoxin
Y Kanai, T Hara, A Imai - Journal of pharmacy and …, 2006 - Wiley Online Library
The involvement of spinal transient receptor potential vanilloid 1 (TRPV1) in formalin‐
evoked pain has remained unclear, because investigation of this kind of pain with selective …
evoked pain has remained unclear, because investigation of this kind of pain with selective …
Proton pump inhibitors prevent gastric antral ulcers induced by NSAIDs via activation of capsaicin-sensitive afferent nerves in mice
H Satoh, Y Akiba, T Urushidani - Digestive Diseases and Sciences, 2020 - Springer
Abstract Background/Aims We examined the effects of proton pump inhibitors (PPIs) on
gastric antral ulcers induced by non-steroidal anti-inflammatory drugs in re-fed mice and the …
gastric antral ulcers induced by non-steroidal anti-inflammatory drugs in re-fed mice and the …