Temperature‐sensitive transient receptor potential vanilloid channels: structural insights into ligand‐dependent activation
L Zubcevic - British Journal of Pharmacology, 2022 - Wiley Online Library
Temperature‐sensitive transient receptor potential vanilloid ion channel subtypes 1–4
(thermoTRPV1–thermoTRPV4) play important roles in a wide range of physiological …
(thermoTRPV1–thermoTRPV4) play important roles in a wide range of physiological …
Capsazepine inhibits low pH-and lactic acid-evoked release of calcitonin gene-related peptide from sensory nerves in guinea-pig heart
A Franco-Cereceda, JM Lundberg - European journal of pharmacology, 1992 - Elsevier
In the isolated perfused guinea-pig heart Iow-pH buffer (pH 5), lactic acid (5 mM), capsaicin
(10− 7 M) and nicotine (10− 4 M) all evoked a clear-cut release of calcitonin gene-related …
(10− 7 M) and nicotine (10− 4 M) all evoked a clear-cut release of calcitonin gene-related …
Effective suppression of Ih and INa caused by capsazepine, known to be a blocker of TRPV1 receptor
A synthetic inhibitor of capsaicin-induced TRPV1 channel activation is called capsazepine
(CPZ). In this study, we aimed to explore the effects of CPZ on hyperpolarization-activated …
(CPZ). In this study, we aimed to explore the effects of CPZ on hyperpolarization-activated …
Role of TRPV1 receptors on panic-like behaviors mediated by the dorsolateral periaqueductal gray in rats
AF Almeida-Santos, FA Moreira, FS Guimarães… - Pharmacology …, 2013 - Elsevier
The transient receptors potential vanilloid type 1 channels (TRPV1) are expressed in several
brain regions related to defensive behaviors, including the dorsolateral periaqueductal gray …
brain regions related to defensive behaviors, including the dorsolateral periaqueductal gray …
Capsaicin-induced activation of fine afferent fibres from rat skin in vitro
N Seno, A Dray - Neuroscience, 1993 - Elsevier
A preparation of the hindpaw-skin together with the saphenous nerve from the adult rat was
maintained in vitro. This was used to characterize the properties of sensory receptors with …
maintained in vitro. This was used to characterize the properties of sensory receptors with …
Effects of TRPV1 receptor antagonists on stimulated iCGRP release from isolated skin of rats and TRPV1 mutant mice
Capsaicin antagonists including ruthenium red, capsazepine and iodo-resiniferatoxin (I-
RTX) have recently been shown to inhibit the activation by noxious heat of the capsaicin …
RTX) have recently been shown to inhibit the activation by noxious heat of the capsaicin …
[HTML][HTML] Constitutive activity of transient receptor potential vanilloid type 1 triggers spontaneous firing in nerve growth factor-treated dorsal root ganglion neurons of …
N Kitamura, E Nagami, Y Matsushita, T Kayano… - IBRO reports, 2018 - Elsevier
Dorsal root ganglion (DRG) neurons cultured in the presence of nerve growth factor (NGF,
100 ng/ml) often show a spontaneous action potential. Underlying mechanisms of this …
100 ng/ml) often show a spontaneous action potential. Underlying mechanisms of this …
Spinal administration of capsazepine inhibits noxious evoked responses of dorsal horn neurons in non-inflamed and carrageenan inflamed rats
S Kelly, V Chapman - Brain research, 2002 - Elsevier
Vanilloid VR1 receptors are located in the dorsal horn of the spinal cord. The aim of the
present study was to determine the role of spinal vanilloid receptors (VR1) during …
present study was to determine the role of spinal vanilloid receptors (VR1) during …
Release of β-endorphin immunoreactivity into ventriculo-cisternal perfusate by lumbar intrathecal capsaicin in the rat
FW Bach, TL Yaksh - Brain research, 1995 - Elsevier
A model employing perfusion of artificial cerebrospinal fluid from the lateral ventricle to the
cisterna magna in the halothane anesthetized rat was used to study β-endorphin release in …
cisterna magna in the halothane anesthetized rat was used to study β-endorphin release in …