[HTML][HTML] The impact of TRPV1 on cancer pathogenesis and therapy: a systematic review
L Li, C Chen, C Chiang, T Xiao, Y Chen… - … journal of biological …, 2021 - ncbi.nlm.nih.gov
The transient receptor potential cation channel subfamily V member 1 (TRPV1) is a
transmembrane protein that can be activated by various physical and chemical stimuli and is …
transmembrane protein that can be activated by various physical and chemical stimuli and is …
Transient receptor potential (TRP) channels: a clinical perspective
Y Kaneko, A Szallasi - British journal of pharmacology, 2014 - Wiley Online Library
Transient receptor potential (TRP) channels are important mediators of sensory signals with
marked effects on cellular functions and signalling pathways. Indeed, mutations in genes …
marked effects on cellular functions and signalling pathways. Indeed, mutations in genes …
Vanilloid (Capsaicin) receptors and mechanisms
A Szallasi, PM Blumberg - Pharmacological reviews, 1999 - ASPET
With regard to the varied, nonculinary uses of hot pepper, there is apparently little new under
the sun. For example, Incas burned dried chili peppers to combat the invading Spaniards by …
the sun. For example, Incas burned dried chili peppers to combat the invading Spaniards by …
Sensory and signaling mechanisms of bradykinin, eicosanoids, platelet-activating factor, and nitric oxide in peripheral nociceptors
Peripheral mediators can contribute to the development and maintenance of inflammatory
and neuropathic pain and its concomitants (hyperalgesia and allodynia) via two …
and neuropathic pain and its concomitants (hyperalgesia and allodynia) via two …
Capsazepine: a competitive antagonist of the sensory neurone excitant capsaicin
1 Capsazepine is a synthetic analogue of the sensory neurone excitotoxin, capsaicin. The
present study shows the capsazepine acts as a competitive antagonist of capsaicin. 2 …
present study shows the capsazepine acts as a competitive antagonist of capsaicin. 2 …
[HTML][HTML] Beyond neuronal heat sensing: diversity of TRPV1 heat-capsaicin receptor-channel functions
YM Shuba - Frontiers in Cellular Neuroscience, 2021 - frontiersin.org
Transient receptor potential vanilloid 1 (TRPV1) is a calcium-permeable ion channel best
known for its ability to be gated by the pungent constituent of red chili pepper, capsaicin, and …
known for its ability to be gated by the pungent constituent of red chili pepper, capsaicin, and …
Activation of epidermal vanilloid receptor-1 induces release of proinflammatory mediators in human keratinocytes
MD Southall, T Li, LS Gharibova, Y Pei, GD Nicol… - … of Pharmacology and …, 2003 - ASPET
During dermal injury and the associated trauma a number of compounds are released that
can mediate the inflammatory response. Determining the cellular mechanisms that initiate …
can mediate the inflammatory response. Determining the cellular mechanisms that initiate …
An N-terminal variant of Trpv1 channel is required for osmosensory transduction
Body fluid homeostasis requires the release of arginine-vasopressin (AVP, an antidiuretic
hormone) from the neurohypophysis. This release is controlled by specific and highly …
hormone) from the neurohypophysis. This release is controlled by specific and highly …
Capsaicin for weight control:“Exercise in a pill”(or just another fad)?
A Szallasi - Pharmaceuticals, 2022 - mdpi.com
Medical management of obesity represents a large unmet clinical need. Animal experiments
suggest a therapeutic potential for dietary capsaicin, the pungent ingredient in hot chili …
suggest a therapeutic potential for dietary capsaicin, the pungent ingredient in hot chili …
Protons: small stimulants of capsaicin-sensitive sensory nerves
S Bevan, P Geppetti - Trends in neurosciences, 1994 - cell.com
The data reviewed in this article suggest that protons should no longer be considered simply
as an unwanted by-product of anaerobic respiration that results from either an accumulation …
as an unwanted by-product of anaerobic respiration that results from either an accumulation …