Saxitoxin (STX) and its 57 analogs are a broad group of natural neurotoxic alkaloids,
commonly known as the paralytic shellfish toxins (PSTs). PSTs are the causative agents of …

The long-lasting interest in bioactive molecules (namely toxins) produced by (microalga)
dinoflagellates has risen in recent years. Exhibiting wide diversity and complexity, said …

Pd-catalyzed sequential hydroamination of readily available 1, 3-enynes is reported. The
redox-neutral process provides an efficient route to synthesize a broad scope of …

The recent prevalence of coronavirus disease in 2019 (COVID-19) has triggered
widespread global health concerns. Antiviral drugs based on phosphoramides have …

Plants represent a rich source of structurally diverse secondary metabolites, which can be
exploited in the development of new clinically important compounds. Indeed, due to their …

Guanidine alkaloids from sponges Monanchora spp. represent diverse bioactive
compounds, however, the mechanisms underlying bioactivity are very poorly understood …

As a type of cyanobacterial toxins, saxitoxin (STX) is receiving great interest due to its
increasing presence in waterbodies. However, the underlying mechanism of STX-induced …

The stereoselective bromofunctionalization of alkenes, particularly the enantioselective
format, has been a subject of intense research in recent years. The ground‐breaking works …

For decades, ligands such as phosphanes or cyclopentadienyl ring derivatives have
dominated Coordination and Organometallic Chemistry. At the same time, alternative …

Combretastatin (CA-4) and its analogues are undergoing several clinical trials for treating
different types of tumors. In this work, the antiproliferative activity of a series of 2 …