[HTML][HTML] Design and evaluation of solid lipid nanoparticles loaded topical gels: repurpose of fluoxetine in diabetic wound healing

F Fatima, M Aleemuddin, MM Ahmed, MK Anwer… - Gels, 2022 - mdpi.com
The current study aimed to prepare a topical gel containing solid lipid nanoparticles (SLNs)
encapsulating fluoxetine for diabetic wound healing effects. Fluoxetine (FX) was loaded into …

[HTML][HTML] Therapeutic role of curcumin in diabetes: an analysis based on bioinformatic findings

A Mahmoudi, SL Atkin, NG Nikiforov, A Sahebkar - Nutrients, 2022 - mdpi.com
Background: Diabetes is an increasingly prevalent global disease caused by the impairment
in insulin production or insulin function. Diabetes in the long term causes both microvascular …

Polymorphisms in glucose homeostasis genes are associated with cardiovascular and renal parameters in patients with diabetic nephropathy

S Mota-Zamorano, LM González, NR Robles… - Annals of …, 2022 - Taylor & Francis
Background Diabetic nephropathy (DN) has become the major cause of end-stage kidney
disease and is associated to an extremely high cardiovascular (CV) risk. Methods We …

[HTML][HTML] Understanding the mechanism of diabetes mellitus in a LRBA-deficient patient

I Hawari, J Ericsson, BSA Kabeer, D Chaussabel… - Biology, 2022 - mdpi.com
Simple Summary Deficiency of lipopolysaccharide responsive beige like anchoring protein
(LRBA) has been reported to cause immunological complications that can be fatal in …

MODY patients carrying mutation in syndromic diabetes genes. An Italian single-center experience

A Marucci, R Di Paola, I Rutigliano, G Fini, S Pezzilli… - Acta Diabetologica, 2023 - Springer
The current molecular diagnostic strategy for monogenic diabetes (MD) outside of infancy
consists in testing 11 Maturity-Onset Diabetes of the Young (MODY) genes, while syndromic …

[HTML][HTML] The Future of Pharmacogenomics Requires New Discoveries and Innovative Education

E Giardina, S Zampatti - Genes, 2022 - mdpi.com
Since the beginning of pharmacology, several variations in responses to drugs have been
recorded. Pharmacodynamics and pharmacokinetics show many interindividual differences …

[HTML][HTML] Two case reports of maturity-onset diabetes of the young type 3 caused by the hepatocyte nuclear factor 1α gene mutation

Q Wen, Y Li, H Shao, J Ma, Y Lin, Y Sun, T Liu - Open Medicine, 2023 - degruyter.com
Maturity-onset diabetes of the young type 3 (MODY3) is a specific type of diabetes mellitus
with inherited impairment of the islet β cell function due to the mutation in the hepatocyte …

Permanent Neonatal Diabetes Mellitus

UD Senarathne, E De Franco, Y Abdelmeguid… - Genetic Syndromes: A …, 2023 - Springer
Permanent neonatal diabetes mellitus (PNDM) is a subtype of neonatal diabetes mellitus
(NDM), a form of monogenic diabetes with wide clinical and genetic heterogeneity …

[HTML][HTML] Corticosteroid-induced bradycardia in multiple sclerosis and maturity-onset diabetes of the young due to hepatocyte nuclear factor 4-alpha mutation: A case …

SY Sohn, SY Kim, IS Joo - World Journal of Clinical Cases, 2022 - ncbi.nlm.nih.gov
BACKGROUND Intravenous steroid pulse therapy is the treatment of choice for acute
exacerbation of multiple sclerosis (MS). Although steroid administration is generally well …

[PDF][PDF] Medicina di precisione: il diabete monogenico

I Rabbone, V Mancioppi, E Pozzi, S Savastio - … : monogenic diabetes. JAMD, 2023 - jamd.it
128 Medicina di precisione: il diabete monogenico Page 1 128 JAMD 2023 | VOL. 26 | N 2
SIMPOSIO Abstract Monogenic diabetes refers to diabetes mellitus caused by a mutation in a …