Signaling pathways in rheumatoid arthritis: implications for targeted therapy

Q Ding, W Hu, R Wang, Q Yang, M Zhu, M Li… - Signal transduction and …, 2023 - nature.com
Rheumatoid arthritis (RA) is an incurable systemic autoimmune disease. Disease
progression leads to joint deformity and associated loss of function, which significantly …

[HTML][HTML] C-reactive protein and implications in rheumatoid arthritis and associated comorbidities

JE Pope, EH Choy - Seminars in arthritis and rheumatism, 2021 - Elsevier
C-reactive protein (CRP) is routinely assessed as a marker of systemic inflammation in
rheumatoid arthritis (RA). However, it is also an immune regulator that plays an important …

Recent advances on signaling pathways and their inhibitors in rheumatoid arthritis

S Liu, H Ma, H Zhang, C Deng, P Xin - Clinical Immunology, 2021 - Elsevier
Rheumatoid arthritis (RA) is characterized by systemic synovitis leading to joint destruction
in which imbalances in pro-inflammatory and anti-inflammatory cytokines promote the …

Oxidative stress in rheumatoid arthritis: What the future might hold regarding novel biomarkers and add‐on therapies

LJS Fonseca, V Nunes-Souza… - Oxidative medicine …, 2019 - Wiley Online Library
Numerous rheumatologic autoimmune diseases, among which rheumatoid arthritis, are
chronic inflammatory diseases capable of inducing multiple cumulative articular and extra …

A randomized, double-blind, placebo-controlled study of daily cannabidiol for the treatment of canine osteoarthritis pain

CD Verrico, S Wesson, V Konduri, CJ Hofferek… - Pain, 2020 - journals.lww.com
1. Background Arthritis is a leading cause of pain, disfigurement, and disability in the United
States where nearly one-quarter of all adults have received an affirmative diagnosis. 2 …

pH-Switched Near-Infrared Fluorescent Strategy for Ratiometric Detection of ONOO in Lysosomes and Precise Imaging of Oxidative Stress in Rheumatoid Arthritis

W Chen, H Liu, F Song, L Xin, Q Zhang… - Analytical …, 2022 - ACS Publications
Rheumatoid arthritis (RA) is well-known as a kind of autoimmune disease, which brings
unbearable pain to the patients by multiple organ complications besides arthritis. To date …

Biogenic selenium nanoparticles: Potential solution to oxidative stress mediated inflammation in rheumatoid arthritis and associated complications

A Rehman, P John, A Bhatti - Nanomaterials, 2021 - mdpi.com
Rheumatoid arthritis (RA) is a common chronic inflammation-mediated disorder having
systematic complications. RA triggers a self-directed inflammatory and immunological …

Ингибиторы Янус-киназ при иммуновоспалительных ревматических заболеваниях: новые возможности и перспективы

ЕЛ Насонов, АМ Лила - Научно-практическая ревматология, 2019 - cyberleninka.ru
Несмотря на большие успехи в диагностике и лечении иммуновоспалительных
ревматических заболеваний (ИВРЗ), приведшие к существенному улучшению прогноза …

Role of oxidative stress in pathophysiology of rheumatoid arthritis: insights into NRF2-KEAP1 signalling

G Kaur, A Sharma, A Bhatnagar - Autoimmunity, 2021 - Taylor & Francis
Rheumatoid arthritis is one of the most prevalent, chronic, inflammatory disorders involving
multiple articular and extra-articular complications. Immune deregulation owing to a …

Immunopathogenesis, early Detection, current therapies and prevention of plantar Fasciitis: A concise review

D Rabadi, S Seo, B Wong, D Chung, V Rai… - International …, 2022 - Elsevier
Plantar fasciitis or the inflammation of the fascial lining on the plantar aspect of the foot
continues to be the leading cause of heel pain for many Americans. Common causes can …