[HTML][HTML] Is Th17-targeted therapy effective in systemic lupus erythematosus?

M Petrić, M Radić - Current issues in molecular biology, 2023 - mdpi.com
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with a broad
spectrum of clinical manifestations. The proposed pathophysiological hypotheses of SLE are …

The gut microbiome in systemic lupus erythematosus: lessons from rheumatic fever

GJ Silverman, DF Azzouz, N Gisch… - Nature Reviews …, 2024 - nature.com
For more than a century, certain bacterial infections that can breach the skin and mucosal
barriers have been implicated as common triggers of autoimmune syndromes, especially …

Systemic Lupus Erythematosus: A Review

CH Siegel, LR Sammaritano - JAMA, 2024 - jamanetwork.com
Importance Systemic lupus erythematosus (SLE) is a chronic autoimmune disease
characterized by inflammation and immune-mediated injury to multiple organ systems …

Biomarkers for systemic lupus erythematosus–a focus on organ damage

H Ding, Y Shen, SM Hong, C Xiang… - Expert Review of Clinical …, 2024 - Taylor & Francis
Introduction Systemic lupus erythematosus (SLE) is complex autoimmune disease with
heterogenous manifestations, unpredictable disease course and response to treatment. One …

Systemic lupus erythematosus and damage: What has changed over the past 20 years?

C Muñoz-Grajales, EB Yilmaz, E Svenungsson… - Best Practice & …, 2023 - Elsevier
The young age of onset and chronic/relapsing nature of systemic lupus erythematosus (SLE)
make SLE patients prone to develop and accrue organ damage as a result of long-standing …

Emerging immunotherapeutic strategies for cutaneous lupus erythematosus: an overview of recent phase 2 and 3 clinical trials

D Lim, J Kleitsch, VP Werth - Expert Opinion on Emerging Drugs, 2023 - Taylor & Francis
Introduction Cutaneous lupus erythematosus (CLE) is an autoimmune disease that is
clinically heterogenous and may occur with or without the presence of systemic lupus …

Autoimmune inflammatory myopathy biomarkers

M Essouma - Clinica Chimica Acta, 2024 - Elsevier
The autoimmune inflammatory myopathy disease spectrum, commonly known as myositis, is
a group of systemic diseases that mainly affect the muscles, skin and lungs. Biomarker …

[HTML][HTML] Lupus dermal fibroblasts are proinflammatory and exhibit a profibrotic phenotype in scarring skin disease

SK Shoffner-Beck, L Abernathy-Close, S Lazar, F Ma… - JCI insight, 2024 - ncbi.nlm.nih.gov
Fibroblasts are stromal cells known to regulate local immune responses important for wound
healing and scar formation; however, the cellular mechanisms driving damage and scarring …

[HTML][HTML] Gluten Intolerance and Its Association With Skin Disorders: A Narrative Review

V Vats, P Makineni, S Hemaida, A Haider, S Subramani… - Cureus, 2023 - ncbi.nlm.nih.gov
Gluten sensitivity is defined as a chronic intolerance to gluten ingestion in genetically
predisposed individuals. The etiology is thought to be immune-mediated and has a variable …

Abnormal energy metabolism in the pathogenesis of systemic lupus erythematosus

S Cao, J Jiang, H Yin, L Wang, Q Lu - International Immunopharmacology, 2024 - Elsevier
Systemic lupus erythematosus (SLE) is a severe autoimmune disease with significant
socioeconomic impact worldwide. Orderly energy metabolism is essential for normal …