This systematic review assesses current molecular targeted therapies for glioblastoma
multiforme (GBM), a challenging condition with limited treatment options. Using PRISMA …

Over 90% of deaths in cancer patients are attributed to tumor drug resistance. Resistance to
therapeutic agents can be due to an innate property of cancer cells or can be acquired …

In this study, we demonstrate that bone mesenchymal stem cell (BMSC)-derived exosomes
alter tumor phenotypes by delivering miR-512-5p. miR-512-5p was downregulated in …

Simple Summary Glioblastoma multiforme is an aggressive grade IV lethal brain tumour with
a median survival of 14 months. Despite surgery to remove the tumour, and subsequent …

Gliomas are the most common brain tumor in adults, and molecularly targeted therapies to
treat gliomas are becoming a frequent topic of investigation. The current state of molecular …

Simple Summary Human neuroblastoma SH-SY5Y is used in neurobiology for studying
various neuropathophysiological processes. In this study, we differentiated neuroblastoma …

Acid-sensing ion channels (ASICs) are voltage-independent H+-gated cation channels
largely expressed in the nervous system of rodents and humans. At least six isoforms …

Acid-sensing ion channel 1a (ASIC1a), a prominent member of the acid-sensing ion channel
(ASIC) superfamily activated by extracellular protons, is ubiquitously expressed throughout …

Background/Aim: Amentoflavone, an effective compound derived from medicinal plants, has
been shown to boost therapeutic efficacy of chemotherapy in non-small cell lung cancer …

Acidic extracellular pH is a major characteristic of tumor tissue, studies suggest that the local
pH value of malignant tumor tissues is between 6.0 and 6.9. Acid-sensing ion channel 1 …