Imbalanced multi-label learning for identifying antimicrobial peptides and their functional types
Motivation: With the rapid increase of infection resistance to antibiotics, it is urgent to find
novel infection therapeutics. In recent years, antimicrobial peptides (AMPs) have been …
novel infection therapeutics. In recent years, antimicrobial peptides (AMPs) have been …
Combining antimicrobial peptides with nanotechnology: an emerging field in theranostics
The emergence of multidrug-resistant pathogens and their rapid adaptation against new
antibiotics is a major challenge for scientists and medical professionals. Different …
antibiotics is a major challenge for scientists and medical professionals. Different …
Predictive model of linear antimicrobial peptides active against gram-negative bacteria
B Vishnepolsky, A Gabrielian, A Rosenthal… - Journal of chemical …, 2018 - ACS Publications
Antimicrobial peptides (AMPs) have been identified as a potential new class of anti-
infectives for drug development. There are a lot of computational methods that try to predict …
infectives for drug development. There are a lot of computational methods that try to predict …
[HTML][HTML] Selective amino acid substitution reduces cytotoxicity of the antimicrobial peptide mastoparan
LN Irazazabal, WF Porto, SM Ribeiro, S Casale… - … et Biophysica Acta (BBA …, 2016 - Elsevier
The emergence of antibiotic-resistant clinical isolates and the decreased rate of
development of new antibiotics are a constant threat to human health. In this context, the …
development of new antibiotics are a constant threat to human health. In this context, the …
Enabling the discovery and virtual screening of potent and safe antimicrobial peptides. Simultaneous prediction of antibacterial activity and cytotoxicity
VV Kleandrova, JM Ruso… - ACS combinatorial …, 2016 - ACS Publications
Antimicrobial peptides (AMPs) represent promising alternatives to fight against bacterial
pathogens. However, cellular toxicity remains one of the main concerns in the early …
pathogens. However, cellular toxicity remains one of the main concerns in the early …
De novo design and in vitro testing of antimicrobial peptides against Gram-negative bacteria
B Vishnepolsky, G Zaalishvili, M Karapetian… - Pharmaceuticals, 2019 - mdpi.com
Antimicrobial peptides (AMPs) have been identified as a potentially new class of antibiotics
to combat bacterial resistance to conventional drugs. The design of de novo AMPs with high …
to combat bacterial resistance to conventional drugs. The design of de novo AMPs with high …
Ubiquicidin-derived peptides selectively interact with the anionic phospholipid membrane
Ubiquicidin (UBI)/ribosomal protein S30 (RS30) is an intracellular protein with antimicrobial
activities against various pathogens. UBI (29–41) and UBI (31–38) are two crucial peptides …
activities against various pathogens. UBI (29–41) and UBI (31–38) are two crucial peptides …
First multitarget chemo-bioinformatic model to enable the discovery of antibacterial peptides against multiple Gram-positive pathogens
A Speck-Planche, VV Kleandrova… - Journal of chemical …, 2016 - ACS Publications
Antimicrobial peptides (AMPs) have emerged as promising therapeutic alternatives to fight
against the diverse infections caused by different pathogenic microorganisms. In this …
against the diverse infections caused by different pathogenic microorganisms. In this …
Short-Chained Linear Scorpion Peptides: A Pool for Novel Antimicrobials
T Panayi, S Diavoli, V Nicolaidou, C Papaneophytou… - Antibiotics, 2024 - mdpi.com
Scorpion venom peptides are generally classified into two main groups: the disulfide
bridged peptides (DBPs), which usually target membrane-associated ion channels, and the …
bridged peptides (DBPs), which usually target membrane-associated ion channels, and the …
[HTML][HTML] Unique thermophoretic behavior of supramolecular assemblies of cationic antimicrobial peptides with anionic small molecule agents
T Juhász, M Quemé-Peña, T Beke-Somfai - Journal of Molecular Liquids, 2023 - Elsevier
Peptidic supramolecules formed via self-and co-assembly are intensively studied and
exploited from materials chemistry to biomedicine. Recently we have demonstrated that …
exploited from materials chemistry to biomedicine. Recently we have demonstrated that …