Current trends and challenges in cancer management and therapy using designer nanomaterials

PN Navya, A Kaphle, SP Srinivas, SK Bhargava… - Nano convergence, 2019 - Springer
Nanotechnology has the potential to circumvent several drawbacks of conventional
therapeutic formulations. In fact, significant strides have been made towards the application …

PAMAM dendrimers as efficient drug and gene delivery nanosystems for cancer therapy

F Abedi-Gaballu, G Dehghan, M Ghaffari, R Yekta… - Applied materials …, 2018 - Elsevier
Drug delivery systems for cancer chemotherapy are employed to improve the effectiveness
and decrease the side-effects of highly toxic drugs. Most chemotherapy agents have …

Antibody‐incorporated nanomedicines for cancer therapy

SY Wu, FG Wu, X Chen - Advanced Materials, 2022 - Wiley Online Library
Antibody‐based cancer therapy, one of the most significant therapeutic strategies, has
achieved considerable success and progress over the past decades. Nevertheless …

[HTML][HTML] Nanotherapeutics: An insight into healthcare and multi-dimensional applications in medical sector of the modern world

M Prasad, UP Lambe, B Brar, I Shah… - Biomedicine & …, 2018 - Elsevier
In recent years nanotechnology has revolutionized the healthcare strategies and envisioned
to have a tremendous impact to offer better health facilities. In this context, medical …

[HTML][HTML] Targeted siRNA lipid nanoparticles for the treatment of KRAS-mutant tumors

S Anthiya, SC Öztürk, H Yanik, E Tavukcuoglu… - Journal of Controlled …, 2023 - Elsevier
K-RAS is a highly relevant oncogene that is mutated in approximately 90% of pancreatic
cancers and 20–25% of lung adenocarcinomas. The aim of this work was to develop a new …

Mitochondria-targeted, nanoparticle-based drug-delivery systems: Therapeutics for mitochondrial disorders

S Buchke, M Sharma, A Bora, M Relekar, P Bhanu… - Life, 2022 - mdpi.com
Apart from ATP generation, mitochondria are involved in a wide range of functions, making
them one of the most prominent organelles of the human cell. Mitochondrial dysfunction is …

Advances in antibody nanoconjugates for diagnosis and therapy: A review of recent studies and trends

J Kadkhoda, M Akrami-Hasan-Kohal… - International journal of …, 2021 - Elsevier
Nowadays, the targeted imaging probe and drug delivery systems are the novel
breakthrough area in the nanomedicine and treatment of various diseases. Conjugation of …

Inhibitory effect of zinc oxide nanorod arrays on breast cancer cells profiled through real‐time cytokines screening by a single‐cell microfluidic platform

P Li, C Wang, J Qiu, F Song, Y Huang, Y Zhang… - …, 2023 - Wiley Online Library
Zinc oxide nanorods have been extensively studied for the specific killing of breast cancer
(BC) cells, and their killing mechanism and anticancer effects have been initially …

Functionalization of nanoparticulate drug delivery systems and its influence in cancer therapy

TA Seidu, PT Kutoka, DO Asante, MA Farooq… - Pharmaceutics, 2022 - mdpi.com
Research into the application of nanocarriers in the delivery of cancer-fighting drugs has
been a promising research area for decades. On the other hand, their cytotoxic effects on …

Glyco-nanoparticles: New drug delivery systems in cancer therapy

H Khan, HR Mirzaei, A Amiri, EK Akkol… - Seminars in cancer …, 2021 - Elsevier
Cancer is known as one of the most common diseases that are associated with high mobility
and mortality in the world. Despite several efforts, current cancer treatment modalities often …