The impact of adjusted treatment on clinical outcomes in patients with severe obesity is
unclear. This study included adults with severe obesity admitted for bloodstream infections …

Background For more effective and safer usage of antibiotics, the dosing strategy should be
individualized based on the patients' characteristics, including race. The aim of this study …

As the prevalence of obesity increases worldwide, clinicians will be more and more
frequently confronted with obese, critically ill patients. Optimal administration of antibiotics is …

Objectives: To evaluate the ability of body-weight-driven renal function assessment (RFA)
formulae to predict on-target elimination rate ranges for gentamicin in patients with varying …

OBJECTIVE: To compare maternal and cord blood penicillin concentrations in women with
and without obesity who are receiving intrapartum group B streptococcus (GBS) prophylaxis …

Six to 23% of patients with acute kidney injury (AKI) in intensive care units (ICU) require
renal support. Continuous renal replacement therapies (CRRT) have become the modality …

Background: The impact of total body weight (TBW) on 30-day mortality associated with
gram-negative bacteremia has not been previously evaluated. Methods: The cohort included …

В настоящее время в развитых странах ожирением страдают от 15 до 50% населения.
Пациенты с ожирением имеют более высокий риск возникновения инфекций, у них …

Background Evidence on pharmacokinetic/pharmacodynamic (PK/PD) alterations and
clinical outcomes in obese patients with serious infections remains limited. This study aimed …

Obezite çok sayıda enfeksiyon hastalığı ile yakından ilişkilidir. Bu enfeksiyonların
yönetiminde obez bireylerde görülen fizyolojik değişiklikler sebebiyle zorluklar …