[HTML][HTML] Hyperkalemic cardioplegia for adult and pediatric surgery: end of an era?

GP Dobson, G Faggian, F Onorati… - Frontiers in …, 2013 - frontiersin.org
Despite surgical proficiency and innovation driving low mortality rates in cardiac surgery, the
disease severity, comorbidity rate, and operative procedural difficulty have increased …

[HTML][HTML] Cardioplegia between evolution and revolution: from depolarized to polarized cardiac arrest in adult cardiac surgery

A Francica, F Tonelli, C Rossetti, I Tropea… - Journal of Clinical …, 2021 - mdpi.com
Despite current advances in perioperative care, intraoperative myocardial protection during
cardiac surgery has not kept the same pace. High potassium cardioplegic solutions were …

[HTML][HTML] Protecting the aged heart during cardiac surgery: the potential benefits of del Nido cardioplegia

SB O'Blenes, CH Friesen, A Ali, S Howlett - The Journal of thoracic and …, 2011 - Elsevier
OBJECTIVE: Aged hearts are more vulnerable than mature hearts to reperfusion injury
during cardiac surgery because of altered cardiomyocyte Ca2+ homeostasis. Inasmuch as …

Mechanisms of ischemic myocardial cell damage assessed by phosphorus-31 nuclear magnetic resonance.

JT Flaherty, ML Weisfeldt, BH Bulkley, TJ Gardner… - Circulation, 1982 - Am Heart Assoc
Phosphorus-31 nuclear magnetic resonance (31P NMR) can estimate tissue intracellular pH
as well as the content of high-energy phosphate metabolites in isolated perfused hearts. We …

Comparison of del Nido and St Thomas cardioplegia solutions in pediatric patients: a prospective randomized clinical trial

S Talwar, A Bhoje, V Sreenivas, N Makhija… - Seminars in Thoracic …, 2017 - Elsevier
We conducted a prospective randomized trial to compare del Nido (DN) cardioplegia with
conventional cold blood cardioplegia (St Thomas [STH]) in pediatric patients. We …

Depletion of myocardial adenosine triphosphate during prolonged untreated ventricular fibrillation: effect on defibrillation success

KB Kern, HS Garewal, AB Sanders, W Janas, J Nelson… - Resuscitation, 1990 - Elsevier
We studied left ventricular endomyocardial adenosine triphospate levels in 13 large mongrel
dogs before and during ventricular fibrillation induced cardiac arrest to assess whether …

Inadequate cardioplegic protection with obstructed coronary arteries

CJ Hilton, W Teubl, M Acker, HJ Levinson… - The Annals of Thoracic …, 1979 - Elsevier
To determine the contribution of complete cardioplegia to the preservation of left ventricular
(LV) function, we put ultrasonic transducers in the anterior and posterior walls of the left …

[HTML][HTML] Stone heart syndrome after prolonged cardioplegia induced cardiac arrest in open-heart surgery–a pilot study on pigs

L Krasniqi, MH Ipsen, HD Schrøder, EK Hejbøl… - Cardiovascular …, 2022 - Elsevier
Abstract Objectives To investigate Stone Heart Syndrome (SHS) as consequence of
prolonged ischemic arrest in an experimental study on pigs in regards to onset of SHS and …

[HTML][HTML] Creatine kinase of heart mitochondria. The progressive loss of enzyme activity during in vivo ischemia and its correlation to depressed myocardial function.

JA Bittl, ML Weisfeldt, WE Jacobus - Journal of Biological Chemistry, 1985 - Elsevier
It is now appreciated that mitochondrial creatine kinase (CKm) may play an important role in
heart high-energy phosphate metabolism and that this isozyme is solubilized in vitro by …

Improved myocardial preservation during global ischemia by continuous retrograde coronary sinus perfusion

SF Bolling, JT Flaherty, BH Bulkley, VL Gott… - The Journal of Thoracic …, 1983 - Elsevier
To investigate whether retrograde continuous low-pressure perfusion of the coronary sinus
could deliver cardioplegic solutions with oxygen and substrate beyond stenoses and result …