[HTML][HTML] Scaffold-facilitated locomotor improvement post complete spinal cord injury: Motor axon regeneration versus endogenous neuronal relay formation
X Li, D Liu, Z Xiao, Y Zhao, S Han, B Chen, J Dai - Biomaterials, 2019 - Elsevier
Complete transected spinal cord injury (SCI) severely influences the quality of life and
mortality rates of animals and patients. In the past decade, many simple and combinatorial …
mortality rates of animals and patients. In the past decade, many simple and combinatorial …
The spinal ependymal zone as a source of endogenous repair cells across vertebrates
Spinal cord injury results in the loss of neurons and axonal connections. In mammals,
including humans, this loss is permanent, but is repaired in other vertebrates, such as …
including humans, this loss is permanent, but is repaired in other vertebrates, such as …
A functional scaffold to promote the migration and neuronal differentiation of neural stem/progenitor cells for spinal cord injury repair
W Liu, B Xu, W Xue, B Yang, Y Fan, B Chen, Z Xiao… - Biomaterials, 2020 - Elsevier
After spinal cord injury (SCI), endogenous neural/progenitor stem cells (NSPCs) were
activated in neural tissue adjacent to the injured segment, but few cells migrated to the injury …
activated in neural tissue adjacent to the injured segment, but few cells migrated to the injury …
Cetuximab modified collagen scaffold directs neurogenesis of injury-activated endogenous neural stem cells for acute spinal cord injury repair
X Li, Y Zhao, S Cheng, S Han, M Shu, B Chen, X Chen… - Biomaterials, 2017 - Elsevier
Studies have shown that endogenous neural stem cells (NSCs) activated by spinal cord
injury (SCI) primarily generate astrocytes to form glial scar. The NSCs do not differentiate …
injury (SCI) primarily generate astrocytes to form glial scar. The NSCs do not differentiate …
Mapping subnational HIV mortality in six Latin American countries with incomplete vital registration systems
Local Burden of Disease HIV Collaborators ladwyer … - Bmc Medicine, 2021 - Springer
Background Human immunodeficiency virus (HIV) remains a public health priority in Latin
America. While the burden of HIV is historically concentrated in urban areas and high-risk …
America. While the burden of HIV is historically concentrated in urban areas and high-risk …
[HTML][HTML] Gsx1 promotes locomotor functional recovery after spinal cord injury
M Patel, Y Li, J Anderson, S Castro-Pedrido, R Skinner… - Molecular therapy, 2021 - cell.com
Promoting residential cells, particularly endogenous neural stem and progenitor cells
(NSPCs), for tissue regeneration represents a potential strategy for the treatment of spinal …
(NSPCs), for tissue regeneration represents a potential strategy for the treatment of spinal …
The activation of dormant ependymal cells following spinal cord injury
FJ Rodriguez-Jimenez, P Jendelova… - Stem Cell Research & …, 2023 - Springer
Ependymal cells, a dormant population of ciliated progenitors found within the central canal
of the spinal cord, undergo significant alterations after spinal cord injury (SCI) …
of the spinal cord, undergo significant alterations after spinal cord injury (SCI) …
Combined polymer-curcumin conjugate and ependymal progenitor/stem cell treatment enhances spinal cord injury functional recovery
R Requejo-Aguilar, A Alastrue-Agudo, M Cases-Villar… - Biomaterials, 2017 - Elsevier
Spinal cord injury (SCI) suffers from a lack of effective therapeutic strategies. Animal models
of acute SCI have provided evidence that transplantation of ependymal stem/progenitor cells …
of acute SCI have provided evidence that transplantation of ependymal stem/progenitor cells …
Bridging the gap with functional collagen scaffolds: tuning endogenous neural stem cells for severe spinal cord injury repair
X Li, J Dai - Biomaterials science, 2018 - pubs.rsc.org
Severe spinal cord injury (SCI) induces massive proliferation of spinal cord neural stem cells
(NSCs), which are considered a promising cell source for therapeutic neural repair …
(NSCs), which are considered a promising cell source for therapeutic neural repair …
Functionalized collagen scaffold implantation and cAMP administration collectively facilitate spinal cord regeneration
X Li, J Han, Y Zhao, W Ding, J Wei, J Li, S Han… - Acta biomaterialia, 2016 - Elsevier
Previous studies have demonstrated that several mechanisms, including numerous
inhibitory molecules, weak neurotrophic stimulation and deficient intrinsic regenerative …
inhibitory molecules, weak neurotrophic stimulation and deficient intrinsic regenerative …