Regulation of gene expression by glycolytic and gluconeogenic enzymes

X Bian, H Jiang, Y Meng, Y Li, J Fang, Z Lu - Trends in cell biology, 2022 - cell.com
Gene transcription and cell metabolism are two fundamental biological processes that
mutually regulate each other. Upregulated or altered expression of glucose metabolic genes …

Myeloperoxidase in the inflamed colon: A novel target for treating inflammatory bowel disease

B Chami, NJJ Martin, JM Dennis, PK Witting - Archives of biochemistry and …, 2018 - Elsevier
Inflammatory bowel disease (IBD) is a debilitating disorder involving inflammation of the
gastrointestinal tract. The incidence of IBD is increasing worldwide. Immunological …

[HTML][HTML] Critical protein GAPDH and its regulatory mechanisms in cancer cells

JY Zhang, F Zhang, CQ Hong, AE Giuliano… - Cancer biology & …, 2015 - ncbi.nlm.nih.gov
Abstract Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), initially identified as a
glycolytic enzyme and considered as a housekeeping gene, is widely used as an internal …

Extracellular Vesicles from BOEC in In Vitro Embryo Development and Quality

R Lopera-Vasquez, M Hamdi, B Fernandez-Fuertes… - PloS one, 2016 - journals.plos.org
To evaluate the effect of conditioned media (CM) and Extracellular Vesicles (EVs) derived
from bovine oviduct epithelial cell (BOEC) lines on the developmental capacity of bovine …

Mixtures of an insecticide, a fungicide and a herbicide induce high toxicities and systemic physiological disturbances in winter Apis mellifera honey bees

H Almasri, DA Tavares, M Pioz, D Sené… - Ecotoxicology and …, 2020 - Elsevier
Multiple pesticides originating from plant protection treatments and the treatment of pests
infecting honey bees are frequently detected in beehive matrices. Therefore, winter honey …

H2S-Induced Sulfhydration: Biological Function and Detection Methodology

D Zhang, J Du, C Tang, Y Huang, H Jin - Frontiers in pharmacology, 2017 - frontiersin.org
At appropriate concentrations, hydrogen sulfide, a well-known gasotransmitter, plays
important roles in both physiology and pathophysiology. Increasing evidence suggests that …

The molecular mechanisms associated with the physiological responses to inflammation and oxidative stress in cardiovascular diseases

S Zhazykbayeva, S Pabel, A Mügge, S Sossalla… - Biophysical …, 2020 - Springer
The complex physiological signal transduction networks that respond to the dual challenges
of inflammatory and oxidative stress are major factors that promote the development of …

Cytosolic thiol switches regulating basic cellular functions: GAPDH as an information hub?

T Hildebrandt, J Knuesting, C Berndt, B Morgan… - Biological …, 2015 - degruyter.com
Cytosolic glyceraldehyde 3-phosphate dehydrogenase (GAPDH, EC 1.2. 1.12) is present in
all organisms and catalyzes the oxidation of triose phosphate during glycolysis. GAPDH is …

Regulation of Glucose Metabolism by NAD+ and ADP-Ribosylation

AK Hopp, P Grüter, MO Hottiger - Cells, 2019 - mdpi.com
Cells constantly adapt their metabolic pathways to meet their energy needs and respond to
nutrient availability. During the last two decades, it has become increasingly clear that …

Targeting glycolysis in non-small cell lung cancer: Promises and challenges

JQ Xu, YL Fu, J Zhang, KY Zhang, J Ma… - Frontiers in …, 2022 - frontiersin.org
Metabolic disturbance, particularly of glucose metabolism, is a hallmark of tumors such as
non-small cell lung cancer (NSCLC). Cancer cells tend to reprogram a majority of glucose …