DNA methylation, ie, addition of methyl group to 5′-carbon of cytosine residues in CpG
dinucleotides, is an important epigenetic modification regulating gene expression, and thus …

Aberrant DNA methylation is an epigenetic hallmark of melanoma, known to play important
roles in melanoma formation and progression. Recent advances in genome-wide …

Epigenetic modifications play a vital role in the preservation of genome integrity and in the
regulation of gene expression. DNA methylation, one of the key mechanisms of epigenetic …

Objectives: Multiple, chronic and repeated trauma exposure in childhood is associated with
adverse mental health outcomes in adulthood. In this paper we synthesise the literature on …

Over the past decades, DNA methylation has been proposed as a molecular mechanism
underlying the positive or negative effects of diet on human health. Despite the number of …

Epigenetics functions as a bridge between host genetic & environmental factors, aiding in
human health and diseases. Many immune-related diseases, including infectious and …

Cancer remains one of the main causes of human mortality despite significant progress in its
diagnostics and therapy achieved in the past decade. Massive hypomethylation of …

DNA methylation (DNAm) is a key mechanism for regulating gene expression in animals
and levels are known to change with age. Recent studies have used DNAm changes as a …

Sequencing technologies have changed not only our approaches to classical genetics, but
also the field of epigenetics. Specific methods allow scientists to identify novel genome-wide …

Epigenetic mechanisms are an underappreciated and often ignored component of an
organism's response to environmental change and may underlie many types of phenotypic …