Protein misfolding and aggregation is observed in many amyloidogenic diseases affecting
either the central nervous system or a variety of peripheral tissues. Structural and dynamic …

Overproduction of oxidants (reactive oxygen species and reactive nitrogen species) in the
human body is responsible for the pathogenesis of some diseases. The scavenging of these …

Since first described in the early 1900s, Alzheimer's disease (AD) has risen exponentially in
prevalence and concern. Research still drives to understand the etiology and pathogenesis …

Neurodegenerative diseases (NDDs) are predicted to be the biggest health concern in this
century and the second leading cause of death by 2050. The main risk factor of these …

Optimized nutrition through supplementation of diet with plant derived phytochemicals has
attracted significant attention to prevent the onset of many chronic diseases including …

Polyphenols are secondary metabolites of plants. They comprise several antioxidant
compounds and they are generally considered to be involved in the defense against human …

Abstract Background Green tea (Camellia sinensis) is a beverage consumed for thousands
of years. Numerous claims about the benefits of its consumption were stated and …

Alzheimer's disease (AD) is a severe, chronic and progressive neurodegenerative disease
associated with memory and cognition impairment ultimately leading to death. It is the …

Oxidative stress is considered as one of the pathogenesis of Alzheimer's disease (AD) and
plays an important role in the occurrence and development of AD. Nuclear factor erythroid 2 …

Resveratrol—a natural polyphenolic compound—was first discovered in the 1940s.
Although initially used for cancer therapy, it has shown beneficial effects against most …