The reductionist approach of dissecting biological systems into their constituents has been
successful in the first stage of the molecular biology to elucidate the chemical basis of …

Network biology has the capability to integrate, represent, interpret, and model complex
biological systems by collectively accommodating biological omics data, biological …

Information theoretic approaches are ubiquitous and effective in a wide variety of
bioinformatics applications. In comparative genomics, alignment-free methods, based on …

Abundance of data on the role of inflammatory immune responses in the progression or
inhibition of hepatocellular carcinoma (HCC) has failed to offer a curative immunotherapy for …

“A Mathematical Theory of Communication” was published in 1948 by Claude Shannon to
address the problems in the field of data compression and communication over (noisy) …

Cellular communication via intracellular signalling pathways is crucial. Expression and
activation of signalling proteins is heterogenous between isogenic cells of the same cell …

We provide a fundamental treatment of the molecular communication channel wherein
“inscribed matter” is transmitted across a spatial gap to provide reliable signaling between a …

Each cancer type has its own molecular signaling network. Analyzing the dynamics of
molecular signaling networks can provide useful information for identifying drug target …

As one of the most important approaches for analyzing the mechanism of fault pervasion,
fault root cause tracing is a powerful and useful tool for detecting the fundamental causes of …

Symmetry and symmetry breaking concepts from physics and biology are applied to the
problem of cancer. Three categories of symmetry breaking in cancer are examined …