Genome analysis using next generation sequencing technologies has revolutionized the
characterization of lactic acid bacteria and complete genomes of all major groups are now …

Streptococcus pyogenes (group A streptococci, GAS) is an exclusive human bacterial
pathogen. The virulence potential of this species is tremendous. Interactions with humans …

The death and lysis of microbial cells leads to the release of cytoplasmic contents, many of
which are rapidly degraded by enzymes. However, some macromolecules survive intact and …

The branched-chain amino acids (BCAAs [Ile, Leu, and Val]) represent important nutrients in
bacterial physiology, with roles that range from supporting protein synthesis to signaling and …

ABSTRACT The Staphylococcus aureus Agr system regulates virulence gene expression by
responding to cell population density (quorum sensing). When an extracellular peptide …

Invasive and noninvasive diseases caused by facultative pathogenic streptococci depend
on their equipment with virulence factors and on their ability to sense and adapt to changing …

AprE and NprE are two major extracellular proteases in Bacillus subtilis whose expression is
directly regulated by several pleiotropic transcriptional factors, including AbrB, DegU, ScoC …

DNases are abundant among the pathogenic streptococci, with most species harbouring
genes for at least one. Despite their prevalence, however, the role for these extracellular …

Group A streptococci produce a wide variety of secreted extracellular products, many of
which are considered virulence factors. The number of these potential virulence factors …

The main role of CodY, a global regulatory protein in most low G+ C gram-positive bacteria,
is in transcriptional repression. To study the functions of CodY in Streptococcus suis …