The blood-brain barrier (BBB) is a critical interface separating the central nervous system
from the peripheral circulation, ensuring brain homeostasis and function. Recent research …

The conduct of molecular and laboratory animal circadian rhythm research has increased
exponentially in the past few decades, such that today investigations are being performed by …

INTRODUCTION—The global prevalence of hypertension is high, and among nonpregnant
adults in the United States, treatment of hypertension is the most common reason for office …

Background Timing drug administration to endogenous circadian rhythms may enhance
treatment efficacy. In the Chronotype sub-study of the Treatment in Morning versus Evening …

Hypertension is the leading risk factor for cardiovascular diseases; however, only one-fifth of
the treated population is believed to attain sufficient blood pressure control level s. A …

The purpose of this review is to synthesize results from studies examining the association
between time-of-day for eating, exercise, and sleep with blood pressure (BP) in adults with …

Objective: Although nocturnal blood pressure (BP) is consistently a stronger predictor to
cardiovascular events and death than daytime BP, specific treatment for nocturnal …

Hypertension and diabetes are important medical conditions that are responsible for a
significant number of deaths globally. Therefore, the objective of this study was to assess the …