[HTML][HTML] Treatment de-intensification strategies for head and neck cancer

JR Kelly, ZA Husain, B Burtness - European Journal of Cancer, 2016 - Elsevier
Increasingly, squamous cell carcinoma of the oropharynx (OPSCC) is attributable to
transformation resulting from high-risk human papillomavirus (HPV) infection. Such cancers …

De-escalation strategies of (chemo) radiation for head-and-neck squamous cell cancers—HPV and beyond

A Rühle, AL Grosu, NH Nicolay - Cancers, 2021 - mdpi.com
Simple Summary HPV-related oropharyngeal squamous cell carcinoma patients have a very
good prognosis but are often suffering from long-term treatment-induced toxicities …

National protocol for model-based selection for proton therapy in head and neck cancer

JA Langendijk, FJP Hoebers… - … journal of particle …, 2021 - meridian.allenpress.com
In the Netherlands, the model-based approach is used to identify patients with head and
neck cancer who may benefit most from proton therapy in terms of prevention of late …

DARS: a phase III randomised multicentre study of dysphagia-optimised intensity-modulated radiotherapy (Do-IMRT) versus standard intensity-modulated …

I Petkar, K Rooney, JWG Roe, JM Patterson… - BMC cancer, 2016 - Springer
Background Persistent dysphagia following primary chemoradiation (CRT) for head and
neck cancers can have a devastating impact on patients' quality of life. Single arm studies …

Revisiting the dose constraints for head and neck OARs in the current era of IMRT

NP Brodin, WA Tomé - Oral oncology, 2018 - Elsevier
Head and neck cancer poses a particular challenge in radiation therapy, whilst being an
effective treatment modality it requires very high doses of radiation to provide effective …

Review of prophylactic swallowing interventions for head and neck cancer

W Yang, W Nie, X Zhou, W Guo, J Mou, J Yong… - International journal of …, 2021 - Elsevier
Background Head and neck cancer treatment destroys nerves and/or organs associated
with swallowing. Previous studies have investigated the efficacy of exercises for muscles …

Predictive factors for chemoradiation-induced oral mucositis and dysphagia in head and neck cancer: a scoping review

AJ Nicol, JCF Ching, VCW Tam, KCK Liu, VWS Leung… - Cancers, 2023 - mdpi.com
Simple Summary Head and neck cancer is the seventh-most prevalent cancer worldwide.
Despite advances in treatment, many patients suffer from chemoradiation-induced oral …

Beyond mean pharyngeal constrictor dose for beam path toxicity in non-target swallowing muscles: dose–volume correlates of chronic radiation-associated dysphagia …

T Dale, K Hutcheson, ASR Mohamed, JS Lewin… - Radiotherapy and …, 2016 - Elsevier
Purpose/objective (s) We sought to identify swallowing muscle dose–response thresholds
associated with chronic radiation-associated dysphagia (RAD) after IMRT for oropharyngeal …

Systematic review of normal tissue complication models relevant to standard fractionation radiation therapy of the head and neck region published after the QUANTEC …

NP Brodin, R Kabarriti, MK Garg, C Guha… - International Journal of …, 2018 - Elsevier
There has recently been an increasing interest in model-based evaluation and comparison
of different treatment options in radiation oncology studies. This is partly driven by the …

[HTML][HTML] Radiation-induced swallowing dysfunction in patients with head and neck cancer: A literature review

YH Chiu, WH Tseng, JY Ko, TG Wang - Journal of the Formosan Medical …, 2022 - Elsevier
Swallowing dysfunction is a prevailing state following radiotherapy in patients with head and
neck cancer. Following the advancement of cancer treatment in recent years, the survival …