Environmental nutrient availability influences T cell metabolism, impacting T cell function
and shaping immune outcomes. Here, we identified ketone bodies (KBs)—including β …

Cardiac fibrosis is a critical pathophysiological process that occurs with diverse types of
cardiac injury. Lipids are the most important bioenergy substrates for maintaining optimal …

Following in the footsteps of genomics and proteomics, metabolomics has revolutionised the
way we investigate and understand biological systems. Rapid development in the last 25 …

Background Ketones are increasingly recognized as an important and possibly oxygen
sparing source of energy in vital organs such as the heart, the brain and the kidneys. Drug …

Decreased nicotinamide adenine dinucleotide (NAD+) levels contribute to various
pathologies such as ageing, diabetes, heart failure and ischemia–reperfusion injury (IRI) …

Chronically adhering to high-fat ketogenic diets or consuming ketone monoester
supplements elicits ketosis. Resulting changes in substrate metabolism appear to be …

Jellyfish stings have become a common injury among fishermen and divers. Severe jellyfish
stings could worsen cardiac function and even cause cardiac complications, ultimately …

The phenomenon of active trans-membrane water cycling (AWC) has emerged in little over
a decade. Here, we consider H2O transport across cell membranes from the origins of its …

Background: Ketones are increasingly recognized as an important and possibly oxygen
sparing source of energy in vital organs such as the heart, the brain and the kidneys. Drug …

Abbreviations: AcAc, acetoacetate; AcAc-CoA, acetoacetyl-CoA; ADP, adenosine
diphosphate; ATP, adenosine triphosphate; βHB, beta-hydroxybutyrate; C, carbon; CO2 …