Exploiting RIG-I-like receptor pathway for cancer immunotherapy
Y Jiang, H Zhang, J Wang, J Chen, Z Guo, Y Liu… - Journal of Hematology & …, 2023 - Springer
RIG-I-like receptors (RLRs) are intracellular pattern recognition receptors that detect viral or
bacterial infection and induce host innate immune responses. The RLRs family comprises …
bacterial infection and induce host innate immune responses. The RLRs family comprises …
The interaction between autophagy, Helicobacter pylori, and gut microbiota in gastric carcinogenesis
Chronic infection with Helicobacter pylori is the primary risk factor for the development of
gastric cancer. Hindering our ability to comprehend the precise role of autophagy during H …
gastric cancer. Hindering our ability to comprehend the precise role of autophagy during H …
Innate immune activation and modulatory factors of Helicobacter pylori towards phagocytic and nonphagocytic cells
L Faass, M Hauke, SC Stein, C Josenhans - Current Opinion in Immunology, 2023 - Elsevier
Highlights•H. pylori is a master influencer of the cell-autonomous immune response.•The H.
pylori Cag type 4 secretion system injects proteins and metabolites.•Bacterial heptose …
pylori Cag type 4 secretion system injects proteins and metabolites.•Bacterial heptose …
Masking of typical TLR4 and TLR5 ligands modulates inflammation and resolution by Helicobacter pylori
SK Pachathundikandi, N Tegtmeyer, S Backert - Trends in Microbiology, 2023 - cell.com
Helicobacter pylori is a paradigm of chronic bacterial infection and is associated with peptic
ulceration and malignancies. H. pylori uses specific masking mechanisms to avoid …
ulceration and malignancies. H. pylori uses specific masking mechanisms to avoid …
Strategies of Helicobacter pylori in evading host innate and adaptive immunity: insights and prospects for therapeutic targeting
J Fan, J Zhu, H Xu - Frontiers in Cellular and Infection Microbiology, 2024 - frontiersin.org
Helicobacter pylori (H. pylori) is the predominant pathogen causing chronic gastric mucosal
infections globally. During the period from 2011 to 2022, the global prevalence of H. pylori …
infections globally. During the period from 2011 to 2022, the global prevalence of H. pylori …
The cytosolic DNA sensor AIM2 promotes Helicobacter‐induced gastric pathology via the inflammasome
RE Dawson, V Deswaerte, AC West… - … and Cell Biology, 2023 - Wiley Online Library
Helicobacter pylori (H. pylori) infection can trigger chronic gastric inflammation perpetuated
by overactivation of the innate immune system, leading to a cascade of precancerous …
by overactivation of the innate immune system, leading to a cascade of precancerous …
Therapeutic approach targeting gut microbiome in gastrointestinal infectious diseases
Z Han, Y Min, K Pang, D Wu - International Journal of Molecular Sciences, 2023 - mdpi.com
While emerging evidence highlights the significance of gut microbiome in gastrointestinal
infectious diseases, treatments like Fecal Microbiota Transplantation (FMT) and probiotics …
infectious diseases, treatments like Fecal Microbiota Transplantation (FMT) and probiotics …
Gut virome profiling identifies an association between temperate phages and colorectal cancer promoted by Helicobacter pylori infection
Colorectal cancer (CRC) is one of the most commonly diagnosed cancers worldwide. While
a close correlation between chronic Helicobacter pylori infection and CRC has been …
a close correlation between chronic Helicobacter pylori infection and CRC has been …
[HTML][HTML] Helicobacter pylori-associated chronic atrophic gastritis and progression of gastric carcinogenesis
NR Lim, WC Chung - The Korean Journal of Gastroenterology, 2023 - kjg.or.kr
Chronic inflammation due to a Helicobacter pylori (H. pylori) infection is a representative
cause of gastric cancer that can promote gastric carcinogenesis by abnormally activating …
cause of gastric cancer that can promote gastric carcinogenesis by abnormally activating …
DNA transport through the dynamic type IV secretion system
ME Ryan, PP Damke, CL Shaffer - Infection and Immunity, 2023 - Am Soc Microbiol
The versatile type IV secretion system (T4SS) nanomachine plays a pivotal role in bacterial
pathogenesis and the propagation of antibiotic resistance determinants throughout microbial …
pathogenesis and the propagation of antibiotic resistance determinants throughout microbial …