Advances and highlights in allergic rhinitis

Y Zhang, F Lan, L Zhang - Allergy, 2021 - Wiley Online Library
Allergic rhinitis (AR) is a growing public health, medical and economic problem worldwide.
The current review describes the major discoveries related to AR during the past 2 years …

Allergen immunotherapy in children user's guide

M Alvaro‐Lozano, CA Akdis, M Akdis… - Pediatric allergy and …, 2020 - Wiley Online Library
Allergen immunotherapy is a cornerstone in the treatment of allergic children. The clinical
efficiency relies on a well‐defined immunologic mechanism promoting regulatory T cells and …

[HTML][HTML] Mechanisms of allergen immunotherapy in allergic rhinitis

G Drazdauskaitė, JA Layhadi, MH Shamji - Current allergy and asthma …, 2021 - Springer
Abstract Purpose of Review Allergic rhinitis (AR) is a chronic inflammatory immunoglobulin
(Ig) E-mediated disease of the nasal mucosa that can be triggered by the inhalation of …

Mechanisms of allergen-specific immunotherapy and allergen tolerance

UC Kucuksezer, C Ozdemir, L Cevhertas… - Allergology …, 2020 - jstage.jst.go.jp
abstract Allergen-specific immunotherapy (AIT) is the mainstay treatment for the cure of
allergic disorders, with depicted efficacy and safety by several trials and meta-analysis. AIT …

[HTML][HTML] Food allergy and intolerance: A narrative review on nutritional concerns

D Gargano, R Appanna, A Santonicola… - Nutrients, 2021 - mdpi.com
Adverse food reactions include immune-mediated food allergies and non-immune-mediated
intolerances. However, this distinction and the involvement of different pathogenetic …

Biomarkers for diagnosis and prediction of therapy responses in allergic diseases and asthma

H Breiteneder, YQ Peng, I Agache, Z Diamant… - Allergy, 2020 - Wiley Online Library
Modern health care requires a proactive and individualized response to diseases,
combining precision diagnosis and personalized treatment. Accordingly, the approach to …

Advances and novel developments in allergic rhinitis

Y Meng, C Wang, L Zhang - Allergy, 2020 - Wiley Online Library
Allergic rhinitis (AR) is an upper airway disease with high prevalence in the world, and
therefore needs to be thoroughly investigated and treated accordingly. Although the …

[HTML][HTML] Trained immunity and tolerance in innate lymphoid cells, monocytes, and dendritic cells during allergen-specific immunotherapy

A Eljaszewicz, F Ruchti, U Radzikowska… - Journal of allergy and …, 2021 - Elsevier
Background Despite the efficacy of allergen-specific immunotherapy (AIT), the role of trained
immunity and tolerance in this process has not been elucidated. Objective Here, we have …

Il-10 producing T and B cells in allergy

T Boonpiyathad, P Satitsuksanoa, M Akdis… - Seminars in …, 2019 - Elsevier
The molecular and cellular mechanisms of allergen tolerance in humans have been
intensively studied in the past few decades. The demonstration of epitope-specific T cell …

The role of Treg cell subsets in allergic disease

T Boonpiyathad, ZC Sözener, M Akdis… - Asian Pacific journal of …, 2020 - zora.uzh.ch
Allergic diseases are caused by a hypersensitivity reaction to an external substance that is
normally not harmful to the body. An imbalance between type 2 immune response and …