CRISPR interference (CRISPRi) enables programmable, reversible, and titratable
repression of gene expression (knockdown) in mammalian cells. Initial CRISPRi-mediated …

Over the last decade, tens of thousands of new long non-coding RNAs (lncRNAs) have been
identified in the human genome. Nevertheless, except for a handful of genes, the genetic …

Numerous long noncoding RNAs (lncRNAs) have been identified as powerful regulators of
human diseases. The lncRNA FOXD3-AS1 is a novel lncRNA that was recently shown to …

Long noncoding RNAs (lncRNAs) account for the largest portion of RNA from the
transcriptome, yet most of their functions remain unknown. Here, we performed two …

Abstract Background Long non-coding RNAs (lncRNAs) are pivotal players in cellular
processes, and their unique cell-type specific expression patterns render them attractive …

Bipolar disorder (BD) patients suffer from severe disability and premature death because of
failure in prognosis, diagnosis, and treatment. Although neural mechanisms of bipolar have …

Aim Cervical cancer has attracted increasing attention in recent years, and the incidence
has shown a trend of younger age. Therefore, it is an effective method to regulate the …

High-throughput genetic screening is useful for discovering critical genes or gene
sequences that trigger specific cell functions and/or phenotypes. Loss-of-function genetic …

Long non-coding RNAs (lncRNAs) account for the largest portion of RNA from the
transcriptome, yet most of their functions remain unknown. Here we performed two …

Introduction Meningiomas are the most common primary central nervous system (CNS)
tumors in adults, representing approximately one-third of all primary adult CNS tumors …