As women enter menopause, the concentration of estrogen and other female hormones
declines. This hormonal decrease has been associated with a number of negative …

Endogenous estrogens are important regulators of cardiovascular homeostasis in
premenopausal women and delay the development of hypertension and coronary artery …

The effects of intrinsic aging on the cutaneous wound healing process are profound, and the
resulting acute and chronic wound morbidity imposes a substantial burden on health …

Premenopausal females have a lower incidence of cardiovascular disease than their male
counterparts, but the mechanism is unclear. Estrogen has been thought to signal through …

We investigated the effects of estrogen on global myocardial ischemia-reperfusion injury in
rats that were ovariectomized (Ovx), sham-operated, or ovariectomized and then given 17β …

We investigated the function of estrogen receptor-α in global myocardial ischemia and
reperfusion injury in male estrogen receptor-α knockout (ERKO) and wild-type mice. Mouse …

Abstract Hemorrhage, trauma, ischemia/reperfusion, burn, and sepsis each lead to cardiac
dysfunction. These insults lead to an inflammatory cascade, which plays an important role in …

Despite significant progress in the care of patients suffering from cardiovascular disease,
there remains a persistent sex disparity in the diagnosis, management, and outcomes of …

In this study, semiquantitative reverse transcription–PCR analysis showed that estrogen
receptor α (ERα) and β (ERβ) mRNAs are developmentally regulated in the rat heart. We …

Cardiovascular disease (CVD), and in particular coronary artery heart disease (CAHD), is
the leading cause of morbidity and mortality in women. Until recently, most of our knowledge …