Development of novel tetrahydroquinoline inhibitors of NLRP3 inflammasome for potential treatment of DSS-induced mouse colitis

Z Dai, X Chen, L An, C Li, N Zhao, F Yang… - Journal of medicinal …, 2020 - ACS Publications
The NLRP3 inflammasome is a critical component of innate immunity, which defends
internal and external threats. However, inappropriate activation of the NLRP3 inflammasome …

[HTML][HTML] Clinical characteristics and treatment of inflammatory bowel disease: a comparison of Eastern and Western perspectives

SJ Park, WH Kim, JH Cheon - World Journal of Gastroenterology …, 2014 - ncbi.nlm.nih.gov
Inflammatory bowel disease (IBD) is a chronic, relapsing intestinal inflammatory disorder
with unidentified causes. Both environmental factors and genetic aspects are believed to be …

[PDF][PDF] Crohn's disease and ulcerative colitis

J Burisch - Occurrence, course and prognosis during the first year …, 2014 - 52.164.122.158
V. Burisch J, Pedersen N, Cukovic-Cavka S, et al. Environmental factors in a population-
based inception cohort of inflammatory bowel disease patients in Europe–An ECCO …

Highlights in IBD epidemiology and its natural history in the paediatric age

M Gasparetto, G Guariso - Gastroenterology research and …, 2013 - Wiley Online Library
Background. The number of patients of all age brackets diagnosed with Inflammatory Bowel
Disease (IBD) has risen dramatically worldwide over the past 50 years. IBD's changing …

[HTML][HTML] Социально-демографическая характеристика, особенности течения и варианты лечения воспалительных заболеваний кишечника в России …

ЕА Белоусова, ДИ Абдулганиева… - Альманах …, 2018 - cyberleninka.ru
Актуальность. Эпидемиологические исследования, проводимые в разных странах,
выявили ряд закономерностей, позволяющих прогнозировать проблемы, связанные с …

Epidemiology of inflammatory bowel diseases from west to east

Z Vegh, Z Kurti, PL Lakatos - Journal of digestive diseases, 2017 - Wiley Online Library
The incidence and prevalence of inflammatory bowel disease (IBD) show considerable
variation over time and across geographical regions. The first studies on the epidemiology of …

[HTML][HTML] Is it time to include older adults in inflammatory bowel disease trials? A call for action

S Vieujean, B Caron, V Jairath, A Benetos… - The Lancet Healthy …, 2022 - thelancet.com
The therapeutic management of older patients with inflammatory bowel disease (IBD) is
challenging, particularly because of the absence of evidence-based guidelines for these …

Hepatic manifestations of inflammatory bowel diseases

S Restellini, O Chazouillères, JL Frossard - Liver International, 2017 - Wiley Online Library
Inflammatory bowel diseases are associated with various hepatobiliary disorders, reported
both in Crohn's disease and ulcerative colitis. They may occur at any moment in the natural …

[HTML][HTML] The prevalence and phenotype in Brazilian patients with inflammatory bowel disease

A Lima Martins, RA Volpato, MP Zago-Gomes - BMC gastroenterology, 2018 - Springer
Background The epidemiology of inflammatory bowel disease (IBD) varies in different
countries. This study aimed to assess phenotype, medications, prevalence and incidence of …

[HTML][HTML] Phenolic compounds impact on rheumatoid arthritis, inflammatory bowel disease and microbiota modulation

R Direito, J Rocha, B Sepodes, M Eduardo-Figueira - Pharmaceutics, 2021 - mdpi.com
Non-communicable chronic diseases (NCDs) are nowadays the principal cause of death,
especially in most industrialized nations. These illnesses have increased exponentially with …