Systemic corticosteroids play an integral role in the management of many inflammatory and
immunologic conditions, but these agents are also associated with serious risks …

Glucocorticoids (GCs) represent the most important and frequently used class of anti-
inflammatory drugs. While the therapeutic effects of GCs have been known and used for …

Severe or therapy-resistant asthma is increasingly recognised as a major unmet need. A
Task Force, supported by the European Respiratory Society and American Thoracic Society …

The GRADE (Grades of Recommendation, Assessment, Development, and Evaluation)
approach provides guidance to grading the quality of underlying evidence and the strength …

Background Corticosteroids have been used for the treatment of inflammatory bowel
disease since the late 1940s. Upwards of 80% of patients may respond acutely to treatment …

Objective To appraise the data on systemic adverse effects of inhaled corticosteroids.
Methods A computerized database search from January 1, 1966, through July 31, 1998 …

Background Antiinflammatory therapies, such as inhaled corticosteroids or nedocromil, are
recommended for children with asthma, although there is limited information on their long …

Inhaled corticosteroids (ICS) are the most effective controllers of asthma. They suppress
inflammation mainly by switching off multiple activated inflammatory genes through …

Inhaled corticosteroids have revolutionized the treatment of asthma and have now become
the mainstay of therapy for patients with chronic disease (1). In a supplement to this journal …

Objective: To develop evidence-based recommendations for the management of systemic
glucocorticoid (GC) therapy in rheumatic diseases. Methods: The multidisciplinary guideline …