[HTML][HTML] A review of the common neurodegenerative disorders: current therapeutic approaches and the potential role of nanotherapeutics
Neurodegenerative disorders are primarily characterized by neuron loss. The most common
neurodegenerative disorders include Alzheimer's and Parkinson's disease. Although there …
neurodegenerative disorders include Alzheimer's and Parkinson's disease. Although there …
Extracellular vesicles: A bright star of nanomedicine
P Wu, B Zhang, DKW Ocansey, W Xu, H Qian - Biomaterials, 2021 - Elsevier
Extracellular vesicles (EVs) have unique structural, compositional, and morphological
characteristics as well as predominant physiochemical stability and biocompatibility …
characteristics as well as predominant physiochemical stability and biocompatibility …
[HTML][HTML] Exosome nanovesicles: a potential carrier for therapeutic delivery
Exosomes are small nanosized biovesicles that form when multivesicular bodies and the
plasma membrane fuse and are released into the surrounding body fluids. They are best …
plasma membrane fuse and are released into the surrounding body fluids. They are best …
Exosomes based strategies for brain drug delivery
Exosome application has emerged as a promising nanotechnology discipline for various
diseases therapeutics and diagnoses. Owing to the natural properties of efficient drug …
diseases therapeutics and diagnoses. Owing to the natural properties of efficient drug …
Potential use of exosomes as diagnostic biomarkers and in targeted drug delivery: progress in clinical and preclinical applications
MN Huda, M Nafiujjaman, IG Deaguero… - ACS biomaterials …, 2021 - ACS Publications
Exosomes are cell-derived vesicles containing heterogeneous active biomolecules such as
proteins, lipids, mRNAs, receptors, immune regulatory molecules, and nucleic acids. They …
proteins, lipids, mRNAs, receptors, immune regulatory molecules, and nucleic acids. They …
[HTML][HTML] Designer exosomes: a new platform for biotechnology therapeutics
Desirable features of exosomes have made them a suitable manipulative platform for
biomedical applications, including targeted drug delivery, gene therapy, cancer diagnosis …
biomedical applications, including targeted drug delivery, gene therapy, cancer diagnosis …
Drug loading techniques for exosome-based drug delivery systems
XM Xi, SJ Xia, R Lu - Die Pharmazie-An International Journal …, 2021 - ingentaconnect.com
Exosomes are bilayer membrane-coated extracellular vesicles measuring between 40 and
100 nm in diameter. As a natural carrier, exosomes have the advantages of low …
100 nm in diameter. As a natural carrier, exosomes have the advantages of low …
[HTML][HTML] Exosomal delivery of therapeutic modulators through the blood–brain barrier; promise and pitfalls
M Heidarzadeh, Y Gürsoy-Özdemir, M Kaya… - Cell & Bioscience, 2021 - Springer
Nowadays, a large population around the world, especially the elderly, suffers from
neurological inflammatory and degenerative disorders/diseases. Current drug delivery …
neurological inflammatory and degenerative disorders/diseases. Current drug delivery …
[HTML][HTML] Enhancing autophagy in Alzheimer's disease through drug repositioning
Alzheimer's disease (AD) is one of the biggest human health threats due to increases in
aging of the global population. Unfortunately, drugs for treating AD have been largely …
aging of the global population. Unfortunately, drugs for treating AD have been largely …
[HTML][HTML] Engineering strategies and optimized delivery of exosomes for theranostic application in nerve tissue
Q Li, X Fu, Y Kou, N Han - Theranostics, 2023 - ncbi.nlm.nih.gov
Severe injuries or diseases affecting the peripheral and central nervous systems can result
in impaired organ function and permanent paralysis. Conventional interventions, such as …
in impaired organ function and permanent paralysis. Conventional interventions, such as …