Hemophagocytic lymphohistiocytosis (HLH) is a severe hyperinflammatory syndrome
induced by aberrantly activated macrophages and cytotoxic T cells. The primary (genetic) …

OBJECTIVE: Hemophagocytic lymphohistiocytosis is a hyperinflammatory syndrome that
often requires critical care support and remains difficult to diagnose. These guidelines are …

Adult-onset Still's disease (AOSD) is a systemic inflammatory disorder with an unknown
cause characterized by high-spiking fever, lymphadenopathy, hepatosplenomegaly …

We performed a comprehensive systematic targeted literature review and used the Delphi
method to formulate expert consensus statements to guide the treatment of adult-onset Still's …

This systematic review (SR) describes the efficacy and safety of biologic disease modifying
anti-rheumatic drugs (bDMARDs) for patients with adult-onset Still's disease (AOSD). Three …

Adult-onset Still's disease (AOSD) is a rare, but characteristic non-familial, multi-genic
systemic auto-inflammatory disorder, characterized by high spiking fever, salmon-like …

Abstract Objectives Adult-onset Still's disease (AOSD) phenotype appears to be
dichotomized in systemic or chronic articular forms. As biologicals and particularly …

ABSTRACT Introduction: Adult-onset Still's disease (AOSD) is a rare multisystem
autoinflammatory disorder of unknown etiology, with clinical and biological similarities with …

Objectives: Hemophagocytic lymphohistiocytosis is a cytokine release syndrome caused by
uncontrolled immune activation resulting in multiple organ failure and death. In this …

Abstract Objectives Adult-onset Still's disease (AOSD) is a rare condition characterized by
fevers, rash, and arthralgia/arthritis; most doctors treating AOSD in the Netherlands treat< 5 …