Novel Mannich bases derived from 1, 2, 4-triazoles: Design, synthesis, characterization, and glutathione S-transferase inhibition properties investigations

O Akyıldırım, H Medetalibeyoğlu, E Oğuz, A Aras… - Journal of Molecular …, 2023 - Elsevier
The reaction of variously substituted 1, 2, 4-triazole derivatives with morpholine and
formaldehyde represents an efficient and easy-to-set synthetic entry toward heterocyclic N …

Synthesis and acetylcholinesterase enzyme inhibitory effects of some novel 4,5-Dihydro-1H-1,2,4-triazol-5-one derivatives; an in vitro and in silico study

H Medetalibeyoğlu, F Türkan, S Manap… - Journal of …, 2023 - Taylor & Francis
In this study, a series of novel Schiff bases (4a-4h) containing 1, 2, 4-triazole structure were
synthesized through a condensation reaction of 3-alkyl (aryl)-4-amino-4, 5-dihydro-1 H-1, 2 …

Synthesis, molecular modeling investigation, molecular dynamic and ADME prediction of some novel Mannich bases derived from 1, 2, 4-triazole, and assessment of …

S Manap, H Medetalibeyoğlu, A Kılıç… - Journal of …, 2023 - Taylor & Francis
A series of biologically active novel Mannich bases containing with a 1 H-1, 2, 4-triazole-5-
one ring were developed to evaluate the cytotoxic activity. For this purpose, the synthesized …

Syntheses, DFT studies and comparatively photovoltaic applications of some pyrene-imine hybrid derivatives

M Erdoğan, A Yeşildağ, H Medetalibeyoğlu, S Horoz - Optical Materials, 2023 - Elsevier
Abstract In this study,(E)-N-phenyl-1 (pyren-1yl) methanimine (3) and a isomeric mixture of
5ZZ and 5EE (1, 4-phenylenebis (1-(pyren-1-yl) methanimine) were synthesized by …

Synthesis, characterization, antioxidant and DFT studies of some novel Schiff base compounds

G Kotan, S Manap, H Yüksek - Journal of Computational Biophysics …, 2022 - World Scientific
A new Schiff base compound and its derivative, 3-cyclopropyl-4-(4-nitrofuran-1-yl)
methyleneamino-4, 5-dihydro-1 H-1, 2, 4-triazol-5-one (3-CNM) and 1-acetly-3-cyclopropyl …

Molecular Modelling, Optical and Electrochemical Properties of Novel 3-Arylazo-thieno[3,2-b]pyranone for Photovoltaic Application

AM Elseman, AS Radwan, MM Makhlouf… - Russian Journal of …, 2022 - Springer
Abstract Three 3-arylazo-thieno [3, 2-b] pyranone dyes HTM 1–3 have been synthesized by
cyclocondensation of ethyl 2-arylazo-(2-phenylthiocarbamoyl) acetate derivatives with ethyl …

Quantum chemical studies on structural, spectroscopic, nonlinear optical, and thermodynamic properties of the 1, 2, 4-triazole compound

H Medetalibeyoğlu, H Yüksek - Heterocyclic Communications, 2021 - degruyter.com
In this study, the structure of 4-[4-(diethylamino)-benzylideneamino]-5-benzyl-2 H-1, 2, 4-
triazol-3 (4 H)-one (DBT) was examined through spectroscopic and theoretical analyses. In …

Investigation on molecular structure and electronic properties of zinc (II) complex with 2-acetylpyridinenicotinichydrazone ligand

G UGURLU, A HARMANKAYA - The Eurasia Proceedings of Science …, 2022 - epstem.net
In the present study, the structural parameter, the electronic and nonlinear optical properties
of three Zn (II) halido complexes of the type [Zn (Hal) 2HL](Hal= Cl, 1; Br, 2; I, 3; HL= 2 …

Experimentical and Gaussian calculations of 3-Ethyl-4-(2-benzenesulfonyloxy)-benzylideneamino-4, 5-dihydro-1H-1, 2, 4-triazol-5-one

F AYTEMIZ, M BEYTUR, H YUKSEK - The Eurasia Proceedings of …, 2022 - epstem.net
3-Ethyl-4-(2-benzenesulfonyloxy)-benzylideneamino-4, 5-dihydro-1H-1, 2, 4-triazol-5-one
has been optimized using the DFT/B3LYP and B3PW91 methods with the 6-311G (d, p) …

Synthesis, Spectroscopic Analysis, Biological Evaluation, and In Silico Studies of Novel Benzenesulfonate-Derived Schiff-Mannich Bases.

A Harmankaya - Journal of the Chemical Society of Pakistan, 2023 - search.ebscohost.com
In the current study, 3-formyl phenyl benzenesulfonate is created by reacting 3-
hydroxybenzaldehyde with benzene sulfonyl chloride, which is aided by triethylamine. Nine …