Nebivolol in the treatment of arterial hypertension

N Olawi, M Krüger, D Grimm, M Infanger… - Basic & Clinical …, 2019 - Wiley Online Library
This MiniReview reports the current knowledge about the treatment of arterial hypertension
with the third‐generation beta‐adrenoceptor antagonist (BAA) nebivolol. Furthermore, it …

Ischemia reperfusion-facilitated sinusoidal endothelial cell injury in liver transplantation and the resulting impact of extravasated platelet aggregation

T Miyashita, S Nakanuma, AK Ahmed, I Makino… - European Surgery, 2016 - Springer
Background The exact sequence of events leading to ultimate hepatocellular damage
following ischemia/reperfusion (I/R) is incompletely understood. In this article, we review a …

[HTML][HTML] Vascular dysfunction in diabetes: The endothelial progenitor cells as new therapeutic strategy

A Georgescu - World journal of diabetes, 2011 - ncbi.nlm.nih.gov
The vascular endothelium is a critical determinant of diabetes-associated vascular
complications, and improving endothelial function is an important target for therapy …

A three-phase approach for the early identification of acute lung injury induced by severe sepsis

T Miyashita, AK Ahmed, S Nakanuma, K Okamoto… - In Vivo, 2016 - iv.iiarjournals.org
A number of studies have reported that acute lung injury (ALI) and acute respiratory distress
syndrome (ARDS) are independent risk factors for organ dysfunction and mortality in …

Effects of transplanted circulating endothelial progenitor cells and platelet microparticles in atherosclerosis development

A Georgescu, N Alexandru, E Andrei… - Biology of the …, 2016 - Wiley Online Library
Background Information Atherosclerosis is an inflammatory disease, in which risk factors
such as hyperlipidemia and hypertension affect the arterial endothelium, resulting in …

Dysfunction of human subcutaneous fat arterioles in obesity alone or obesity associated with Type 2 diabetes

A Georgescu, D Popov, A Constantin… - Clinical …, 2011 - portlandpress.com
The aim of the present study was to examine the effects of obesity alone and obesity
associated with Type 2 diabetes on the structure, vascular reactivity and response to insulin …

The effects of newer beta-adrenoceptor antagonists on vascular function in cardiovascular disease

M Wehland, J Grosse, U Simonsen… - Current vascular …, 2012 - ingentaconnect.com
This review provides a systematic overview of the influence of the third generation beta-
adrenoceptor antagonists on vascular and/or endothelial function at a cellular level as well …

The promise of EPC-based therapies on vascular dysfunction in diabetes

A Georgescu, N Alexandru, A Constantinescu… - European journal of …, 2011 - Elsevier
Diabetes mellitus is one of the most common metabolic diseases in the world and the
vascular dysfunction represents a challenging clinical problem. In diabetes, endothelial cells …

Nebivolol: An Endothelium-Friendly Selective β: 1:-Adrenoceptor Blocker

Y Gao, PM Vanhoutte - Journal of Cardiovascular Pharmacology, 2012 - journals.lww.com
Nebivolol is a highly selective β 1-adrenoceptor blocker, which also stimulates endothelial
nitric oxide synthase and scavenges reactive oxygen species (ROS). These characteristics …

Irbesartan administration therapeutically influences circulating endothelial progenitor cell and microparticle mobilization by involvement of pro-inflammatory cytokines

A Georgescu, N Alexandru, M Nemecz… - European journal of …, 2013 - Elsevier
Circulating microparticles (MPs) and endothelial progenitor cells (EPCs) correlate with
endothelial dysfunction and contribute to the pathogenesis of atherosclerosis. In this context …