Over the past decade, the therapeutic potential of nanomaterials as novel drug delivery
systems complementing conventional pharmacology has been widely acknowledged …

More than fifty years after the 3Rs definition and despite the continuous implementation of
regulatory measures, animals continue to be widely used in basic research. Their use …

It is crucial for molecular dynamics simulations of biomembranes that the force field
parameters give a realistic model of the membrane behavior. In this study, we examined the …

Molecular simulations of biological membranes and proxies thereof are entering a new era
characterized by several key aspects. Progress starts with the realization that the outcome of …

The Suzuki–Miyaura reaction between the aryl halide (1) and the phenyl boronic acid (2), in
the presence of the palladium (0) complex (3) as catalyst, gives the cross-coupling product …

A wide range of biomaterials and engineered cell surfaces are composed of bioconjugates
embedded in liposome membranes, surface-immobilized bilayers, or the plasma …

Background Nanomedicine and the pharmaceutical industry demand the investigation of
new biomaterials to improve drug therapies. Combinations of lipids, proteins, and polymers …

Open-source MD simulation tools provide academics and low-income countries with the
ability to compete in drug discovery advancements. Gromacs is a well-known and …

Fluoxetine, which is a well-known antidepressant drug, is studied in hydrated cholesterol-
free and cholesterol-containing lipid bilayers through unbiased and biased atomistic …

Liposome-based technologies derived from lipids and polymers (eg, PEGylated liposomes)
have been recognized because of their applications in nanomedicine. However, since such …