Hypothalamic kisspeptin neurons serve as the nodal regulatory centre of reproductive
function. These neurons are subjected to a plethora of regulatory factors that ultimately affect …

The bioactive peptides galanin, spexin and kisspeptin have a common ancestral origin and
their pathophysiological roles are increasingly the subject of investigation. Evidence …

Endometriosis and polycystic ovary syndrome (PCOS) are two common female reproductive
disorders with a significant impact on the health and quality of life of women affected. A …

Kisspeptin (KP) and neurokinin B (NKB) are neuropeptides that govern the reproductive
endocrine axis through regulating hypothalamic gonadotropin-releasing hormone (GnRH) …

Genome-wide association studies (GWASs) have identified genetic loci associated with the
risk of Alzheimer's disease (AD), but the molecular mechanisms by which they confer risk …

Nonalcoholic fatty liver disease (NAFLD), the most common liver disease, has become a
silent worldwide pandemic. The incidence of NAFLD correlates with the rise in obesity, type …

Obesity is one of major risk factors increasing chronic diseases including type II diabetes,
cardiovascular diseases, and hypertension. The effects of epigallocatechin gallate (EGCG) …

Background & Aims Acute liver failure (ALF) is a life-threatening disease characterised by
high-grade inflammation and immunoparesis, which is associated with a high incidence of …

Although the pathogenesis of Polycystic Ovary Syndrome (PCOS) is still unclear, the
disturbance of hypothalamic-pituitary-gonadal (HPG) axis is suspected to be the main culprit …

Abstract BACKGROUND Glucagon-like peptide-1 (GLP-1) receptor agonists (GLP-1 RAs)
have become firmly established in the treatment of type 2 diabetes and obesity, disorders …