The inflammatory bowel disease (IBD) is incurable, chronic, recrudescent disorders in the
inflamed intestines. Current clinic treatments are challenged by systemic exposure-induced …

Polymeric micellar drug carriers have emerged as effective tools to enhance the solubility
and bioavailability of hydrophobic drugs. These micelles possess a nano size structure that …

Diabetic osteoporosis (DOP) is a significant complication that poses continuous threat to the
bone health of patients with diabetes; however, currently, there are no effective treatment …

Mutual interference between surface ligands on multifunctional nanoparticles remains a
significant obstacle to achieving optimal drug-delivery efficacy. Here, we develop ligand …

Quantum chemical density functional theory (DFT) calculations were performed to examine
features of metal-doped graphene (MG) models for adsorbing the popular ibuprofen (IBU) …

Although nano-systems can promote the cellular internalization, polymeric nanoparticles
(NPs) are easily to be destroyed or eliminated in the gastrointestinal tract, which leads to …

Dysfunction of the intestinal mucosal immune system and dysbiosis of the intestinal
microflora can induce inflammatory bowel disease. However, drug-mediated clinical …

One of the effective treatment options for intracranial aneurysms is stent-assisted coiling.
Though, previous works have demonstrated that stent usage would result in the deformation …

The occurrence and development of inflammatory bowel diseases (IBDs) are inextricably
linked to the excessive production of reactive oxygen species (ROS). Thus, there is an …

Intestinal inflammation, such as ulcerative colitis (UC), is a condition in which there is
chronic or recurring inflammation of the gastrointestinal tract. Designing safe, effective, and …