Macrophage polarity and disease control
S Kadomoto, K Izumi, A Mizokami - International Journal of Molecular …, 2021 - mdpi.com
Macrophages are present in most human tissues and have very diverse functions. Activated
macrophages are usually divided into two phenotypes, M1 macrophages and M2 …
macrophages are usually divided into two phenotypes, M1 macrophages and M2 …
Chemokines in colon cancer progression
SN Jia, YB Han, R Yang, ZC Yang - Seminars in cancer biology, 2022 - Elsevier
Colon cancer is a major human cancer accounting for about a tenth of all cancer cases thus
making it among the top three cancers in terms of incidence as well as mortality. Metastasis …
making it among the top three cancers in terms of incidence as well as mortality. Metastasis …
Highly‐metastatic colorectal cancer cell released miR‐181a‐5p‐rich extracellular vesicles promote liver metastasis by activating hepatic stellate cells and remodelling …
S Zhao, Y Mi, B Zheng, P Wei, Y Gu… - Journal of …, 2022 - Wiley Online Library
Liver metastasis of colorectal cancer (CRLM) is the most common cause of CRC‐related
mortality, and is typically caused by interactions between CRC cells and the tumour …
mortality, and is typically caused by interactions between CRC cells and the tumour …
[HTML][HTML] Immunotherapy for hepatocellular carcinoma: Current status and future perspectives
DS Mandlik, SK Mandlik… - World Journal of …, 2023 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is one of the world's deadliest and fastest-growing tumors,
with a poor prognosis. HCC develops in the context of chronic liver disease. Curative …
with a poor prognosis. HCC develops in the context of chronic liver disease. Curative …
Antigen dominance hierarchies shape TCF1+ progenitor CD8 T cell phenotypes in tumors
CD8 T cell responses against different tumor neoantigens occur simultaneously, yet little is
known about the interplay between responses and its impact on T cell function and tumor …
known about the interplay between responses and its impact on T cell function and tumor …
PMN-MDSCs modulated by CCL20 from cancer cells promoted breast cancer cell stemness through CXCL2-CXCR2 pathway
R Zhang, M Dong, J Tu, F Li, Q Deng, J Xu… - Signal transduction and …, 2023 - nature.com
Our previous studies have showed that CC motif chemokine ligand 20 (CCL20) advanced
tumor progression and enhanced the chemoresistance of cancer cells by positively …
tumor progression and enhanced the chemoresistance of cancer cells by positively …
Single-cell RNA-sequencing reveals radiochemotherapy-induced innate immune activation and MHC-II upregulation in cervical cancer
Radiochemotherapy (RCT) is a powerful treatment for cervical cancer, which affects not only
malignant cells but also the immune and stromal compartments of the tumor. Understanding …
malignant cells but also the immune and stromal compartments of the tumor. Understanding …
Tumor-associated macrophages and ovarian cancer: implications for therapy
Simple Summary Ovarian cancer is a highly lethal female malignancy with high rates of
advanced stage and recurrent disease. Ovarian cancer is characterized as poorly …
advanced stage and recurrent disease. Ovarian cancer is characterized as poorly …
Fusobacterium nucleatum promotes colorectal cancer metastasis through miR-1322/CCL20 axis and M2 polarization
C Xu, L Fan, Y Lin, W Shen, Y Qi, Y Zhang, Z Chen… - Gut …, 2021 - Taylor & Francis
Colorectal cancer (CRC) is one of the most common malignant tumors and is associated
with Fusobacterium nucleatum (F. nucleatum, Fn) infection. In this study, we explored the …
with Fusobacterium nucleatum (F. nucleatum, Fn) infection. In this study, we explored the …
Tumor immunogenic cell death as a mediator of intratumor CD8 T-cell recruitment
The success of anticancer treatments relies on a long-term response which can be mediated
by the immune system. Thus, the concept of immunogenic cell death (ICD) describes the …
by the immune system. Thus, the concept of immunogenic cell death (ICD) describes the …