Direct Cell Radiolabeling for in Vivo Cell Tracking with PET and SPECT Imaging

PJ Gawne, F Man, PJ Blower… - Chemical reviews, 2022 - ACS Publications
The arrival of cell-based therapies is a revolution in medicine. However, its safe clinical
application in a rational manner depends on reliable, clinically applicable methods for …

Recent advances in cation sensing using aggregation-induced emission

MH Chua, H Zhou, Q Zhu, BZ Tang… - Materials Chemistry …, 2021 - pubs.rsc.org
The discovery of the aggregation-induced emission (AIE) phenomenon about two decades
ago has ever since changed our mutual understanding of the aggregation of organic …

In vitro and in vivo anticancer activity of tridentate thiosemicarbazone copper complexes: Unravelling an unexplored pharmacological target

M Carcelli, M Tegoni, J Bartoli, C Marzano… - European Journal of …, 2020 - Elsevier
Certain metal complexes can have a great antitumor activity, as the use of cisplatin in
therapy has been demonstrating for the past fifty years. Copper complexes, in particular …

[HTML][HTML] Environmental stress in chickens and the potential effectiveness of dietary vitamin supplementation

F Akinyemi, D Adewole - Frontiers in Animal Science, 2021 - frontiersin.org
Environmental stressors can promote the vulnerability of animals to infections; it is therefore,
essential to understand how stressors affect the immune system, the adaptive capacity of …

ATP7A-regulated enzyme metalation and trafficking in the menkes disease puzzle

N Horn, P Wittung-Stafshede - Biomedicines, 2021 - mdpi.com
Copper is vital for numerous cellular functions affecting all tissues and organ systems in the
body. The copper pump, ATP7A is critical for whole-body, cellular, and subcellular copper …

Chelating principles in Menkes and Wilson diseases: Choosing the right compounds in the right combinations at the right time

N Horn, LB Møller, VM Nurchi, J Aaseth - Journal of inorganic biochemistry, 2019 - Elsevier
Dysregulation of copper homeostasis in humans is primarily found in two genetic diseases
of copper transport, Menkes and Wilson diseases, which show symptoms of copper …

Selenium homeostasis in human brain cells: Effects of copper (II) and Se species

S Raschke, F Ebert, AP Kipp, JF Kopp… - Journal of Trace …, 2023 - Elsevier
Background Both essential trace elements selenium (Se) and copper (Cu) play an important
role in maintaining brain function. Homeostasis of Cu, which is tightly regulated under …

Chemical background of silver nanoparticles interfering with mammalian copper metabolism

AN Skvortsov, EY Ilyechova, LV Puchkova - Journal of Hazardous Materials, 2023 - Elsevier
The rapidly increasing application of silver nanoparticles (AgNPs) boosts their release into
the environment, which raises a reasonable alarm for ecologists and health specialists. This …

Ratiometric two-photon microscopy reveals attomolar copper buffering in normal and Menkes mutant cells

MT Morgan, D Bourassa… - Proceedings of the …, 2019 - National Acad Sciences
Copper is controlled by a sophisticated network of transport and storage proteins within
mammalian cells, yet its uptake and efflux occur with rapid kinetics. Present as Cu (I) within …

IoT-Orchestration based nanogrid energy management system and optimal time-aware scheduling for efficient energy usage in nanogrid

F Qayyum, H Jamil, F Jamil, S Ahmad… - International Journal of …, 2022 - Elsevier
Abstract Internet of Things (IoT) has brought an immense revolution in diverse fields related
to mission-critical systems including healthcare and navigation systems. We argue that the …