The penultimate effectors of the Hippo signaling pathways YAP and TAZ, are transcriptional
co-activator proteins that play key roles in many diverse biological processes, ranging from …

The aquaporins (AQPs) are a family of small integral membrane proteins that facilitate the
bidirectional transport of water across biological membranes in response to osmotic …

The establishment of cell identity during embryonic development involves the activation of
specific gene expression programmes and is underpinned by epigenetic factors including …

The vertebrate 'neural plate border'is a transient territory located at the edge of the neural
plate containing precursors for all ectodermal derivatives: the neural plate, neural crest …

The ability of the pluripotent epiblast to contribute progeny to all three germ layers is thought
to be lost after gastrulation. The later-forming neural crest (NC) rises from ectoderm and it …

Craniofacial development, one of the most complex sequences of developmental events in
embryology, features a uniquely transient, pluripotent stem cell-like population known as the …

Neural crest (NC) cells migrate throughout vertebrate embryos to give rise to a huge variety
of cell types, but when and where lineages emerge and their regulation remain unclear. We …

Adipose tissues, including white, beige, and brown adipose tissue, have evolved to be
highly dynamic organs. Adipose tissues undergo profound changes during development …

Craniofacial anomalies are among the most common of birth defects. The pathogenesis of
craniofacial anomalies frequently involves defects in the migration, proliferation, and fate of …

Schwann cells are glial cells of the peripheral nervous system. They exist in several
subtypes and perform a variety of functions in nerves. Their derivation and culture in vitro are …